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Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
  • 30 min drive from Lewis and Clark Interpretive Center
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,053 reviews)
"We used the valet service - VERY smooth process / We don't travel to larger cities too often, the staff at this property were wonderful, answered all of our questions, and made this experience great. Walking distance to the Arch too. So convenient."

Reviewed on May 19, 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
  • 33 min drive from Lewis and Clark Interpretive Center
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (3,190 reviews)
"Clayton Plaza has always been my place to stay the last four years my son was in college at WashU. It is close to the campus. You can walk to a few restaurants nearby. The staff are always nice and rooms are perfect for a short stay. I would definitely recommend"

Reviewed on May 20, 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
  • 30 min drive from Lewis and Clark Interpretive Center
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,958 reviews)
"The staff was really helpful, patient and informative. Location is convenient. Good value. Clean room"

Reviewed on May 20, 2026

Pear Tree Inn St. Louis Near Union Station
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
  • 23 min drive from Lewis and Clark Interpretive Center
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,087 reviews)
"Staff was friendly and the property was nice and clean."

Reviewed on May 19, 2026

Renaissance St. Louis Airport Hotel
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
  • 31 min drive from Lewis and Clark Interpretive Center
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,379 reviews)
"Parking was a very big issue here! We have a cargo van and it doesn't fit in the garage. Website has now been updated with this information, but it was a nightmare every night of the 4 we were here. Hotel is under remodeling which made parking even more difficult. Food buffet was ok. Breakfast is ..."

Reviewed on May 19, 2026

Drury Inn & Suites St. Louis Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
  • 30 min drive from Lewis and Clark Interpretive Center
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,844 reviews)
"I loved the art museum, the bar and cafe. The staff were so friendly and helpful"

Reviewed on May 20, 2026

21C Museum Hotel St Louis
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
  • 31 min drive from Lewis and Clark Interpretive Center
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9.4/10 Exceptional! (1,185 reviews)
"Excellent customer service and check in. The room was so nice, bed very comfortable and amenities were great! Will stay again!"

Reviewed on May 19, 2026

Live by Loews - St.Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
  • 31 min drive from Lewis and Clark Interpretive Center
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.6/10 Exceptional! (3,431 reviews)
"I loved my stay at Drury. We were so close to the Arche, walked out the front door, turned right, turned right again, and walked straight at the Arch. It was such a nice treat to have breakfast and afternoon food provided for free. And let me tell you the people who run the food portion, cleaning ..."

Reviewed on May 20, 2026

Drury Plaza Hotel St. Louis at the Arch
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
  • 30 min drive from Lewis and Clark Interpretive Center
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,278 reviews)
"Beds were comfy. Room was clean. Parking fee was steep. Location great."

Reviewed on May 18, 2026

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
  • 24 min drive from Lewis and Clark Interpretive Center
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (2,986 reviews)
"Great stay for one night"

Reviewed on May 20, 2026

Pear Tree Inn St. Louis Airport
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd St. Louis MO
  • 48 min drive from Lewis and Clark Interpretive Center
Book a stay at this business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,565 reviews)
"Room was clean. The curtains were hideous. They were absolutely too long for the windows. It through the entire vibe of the room off. They were super long heavy draperies. That needs to be fixed. There is no way. This is not how the room looked in the picture. Also, my room was switched because the ..."

Reviewed on May 20, 2026

River City Casino & Hotel
Forest Park Hotel by MDR

Forest Park Hotel by MDR

3 out of 5
5915 Wilson Ave St. Louis MO
  • 35 min drive from Lewis and Clark Interpretive Center
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
Forest Park Hotel by MDR
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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