Hotels Near
Mission Bay

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Featured Mission Bay Hotels

The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
8.8/10 Excellent! (3,858 reviews)
Clean rooms, friendly staff close to many things to do definitely enjoyed my stay

Reviewed on Nov 13, 2025

The Dana on Mission Bay
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (2,325 reviews)
It’s a nice place to spend the night. Room is clean and amenities are great. The only thing I hope they improve on was to have more than 1 staff on the front desk? I tried calling the receptionist twice but no answer so I decided to go into the lobby and found out the receptionist was helping another ...

Reviewed on Nov 13, 2025

Paradise Point Resort & Spa
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd San Diego CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.4/10 Very Good! (1,558 reviews)
view was very scenic. The great attentiveness given at the restaurant Pelican's on the Bay for food and drinks ordered. The service was very good. The staff went out of their way to meet our needs in a timely manner. That was the highlight of our stay. The fast service was very appreciated due the ...

Reviewed on Nov 10, 2025

Hyatt Regency Mission Bay Spa and Marina
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
8.4/10 Very Good! (1,299 reviews)
great stay! Food was great and my kids loved the pool and location

Reviewed on Nov 10, 2025

San Diego Mission Bay Resort
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8/10 Very Good! (2,172 reviews)
Room was spotless, nice room. Good area

Reviewed on Nov 15, 2025

Hilton San Diego Mission Valley
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
9/10 Wonderful! (2,930 reviews)
Room was clean and spacious

Reviewed on Nov 14, 2025

Legacy Resort Hotel & Spa
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Mission Bay and Port of ...
9/10 Wonderful! (293 reviews)
Hotel, inside and outside clean. Rooms, lobby and gym and hallways clean, spacious, sufficient elevators. Modern, new and spacious. Gym was real nice with good equipment. The staff was real professional and friendly. Breakfast was delicious. The streets/areas/traffic near me of the hotel were ...

Reviewed on Nov 15, 2025

Hampton Inn & Suites by Hilton San Diego SeaWorld
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
8.8/10 Excellent! (3,075 reviews)
We did not experience breakfast but everything else about the hotel was fantastic. The staff was extremely friendly and helpful. You can walk to all the restaurants and lounges.

Reviewed on Nov 14, 2025

Hard Rock Hotel San Diego
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4 out of 5
1646 Front St San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.2/10 Very Good! (1,217 reviews)
The front desk were very helpful, they placed us in a city view room. Gave us snacks and water when we got there. The hotel and rooms were very clean. Great customer service. My daughter loved the pool. Definitely will would reserve this hotel again. Thank You for a good experience.

Reviewed on Nov 14, 2025

Courtyard by Marriott San Diego Downtown Little Italy
Pendry San Diego

Pendry San Diego

5 out of 5
550 J Street San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in San Diego. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,003 reviews)
Beautiful hotel. Beat all expectations

Reviewed on Nov 12, 2025

Pendry San Diego
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,032 reviews)
Older hotel. Clean. Convenient location. Friendly staff.

Reviewed on Nov 14, 2025

Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
8.2/10 Very Good! (2,191 reviews)
Very clean and safe hotel. We loved the pool area and great happy hour specials. The room smelled a little musty but it was very clean. Definitely good value for your money.

Reviewed on Nov 11, 2025

Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Mission Bay

San Diego is a city that has a lot going on, but you have your sights set on Mission Bay. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Mission Bay has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Mission Bay hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of San Diego so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Mission Bay underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Mission Bay city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Mission Bay cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Mission Bay at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $112
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Mission Bay hotel you want, book it, and never look back. Because your great escape is ahead of you.