Search for Cheap Deals on4 Star Hotels in Lake Nona Medical City
Check Last Minute Lake Nona Medical City Hotel Deals
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Featured 4 Star Lake Nona Medical City Hotels

Fully refundableReserve now, pay when you stay
The price is $139 per night from Apr 22 to Apr 23
$139
includes taxes & fees
Apr 22 - Apr 23
Stay at this 4-star family-friendly resort in Orlando. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the breakfast and the pool in our ...

Fully refundableReserve now, pay when you stay
The price is $227 per night from Apr 20 to Apr 21
$227
includes taxes & fees
Apr 20 - Apr 21
Stay at this 4.5-star luxury hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...

Fully refundableReserve now, pay when you stay
The price is $244 per night from Apr 21 to Apr 22
$244
includes taxes & fees
Apr 21 - Apr 22
Book a stay at this luxury hotel in Orlando. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the restaurant in our ...
Save an average of 15% on thousands of hotels when you're signed in

Fully refundableReserve now, pay when you stay
The price is $235 per night from Apr 21 to Apr 22
$235
includes taxes & fees
Apr 21 - Apr 22
Stay at this 4-star eco-certified hotel in Orlando. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...

Fully refundableReserve now, pay when you stay
The price is $268 per night from Apr 21 to Apr 22
$268
includes taxes & fees
Apr 21 - Apr 22
Stay at this 4-star beach hotel in Lake Buena Vista. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the restaurant ...

The price is $154 per night from Apr 20 to Apr 21
$154
includes taxes & fees
Apr 20 - Apr 21
Stay at this 4-star spa hotel in Orlando. Enjoy free parking, 7 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...

Fully refundableReserve now, pay when you stay
The price is $127 per night from May 7 to May 8
$127
includes taxes & fees
May 7 - May 8
Book a stay at this spa hotel in Orlando. Enjoy 2 outdoor pools, a full-service spa, and 2 hot tubs. Our guests praise the pool and the bar in our reviews. Popular ...

Fully refundableReserve now, pay when you stay
The price is $104 per night from May 4 to May 5
$104
includes taxes & fees
May 4 - May 5
Stay at this 4-star family-friendly hotel in Orlando. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in ...

Fully refundableReserve now, pay when you stay
The price is $99 per night from Apr 20 to Apr 21
$99
includes taxes & fees
Apr 20 - Apr 21
Stay at this 4-star family-friendly hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and breakfast (surcharge). Our guests praise the pool and the helpful ...

Fully refundableReserve now, pay when you stay
The price is $110 per night from Apr 10 to Apr 11
$110
includes taxes & fees
Apr 10 - Apr 11
Stay at this 4-star family-friendly hotel in Orlando. Enjoy free WiFi, breakfast (surcharge), and a free theme park shuttle. Our guests praise the pool and the ...

Fully refundableReserve now, pay when you stay
The price is $215 per night from Apr 21 to Apr 22
$215
includes taxes & fees
Apr 21 - Apr 22
Stay at this 4-star spa resort in Orlando. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. ...

Fully refundableReserve now, pay when you stay
The price is $237 per night from May 7 to May 8
$237
includes taxes & fees
May 7 - May 8
Stay at this 4-star spa resort in Kissimmee. Enjoy 3 outdoor pools, a full-service spa, and 3 restaurants. Our guests praise the pool and the restaurant in our ...
Don't see what you're looking for?
See all available properties in Lake Nona Medical City
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Hotel Options in Lake Nona Medical City
- Hotels with a Pool in Lake Nona Medical City
- Hotels with Free Parking in Lake Nona Medical City
- Family Hotels in Lake Nona Medical City
- Hotels with Free Airport Shuttle in Lake Nona Medical City
- Apartment Hotel in Lake Nona Medical City
- Romantic Hotels in Lake Nona Medical City
- Pet-friendly Hotels in Lake Nona Medical City
- Luxury Hotels in Lake Nona Medical City
Popular Lake Nona Medical City Hotels
- Holiday Inn Resort Orlando Suites - Waterpark by IHG
- Hyatt Regency Orlando International Airport
- Rosen Inn at Pointe Orlando
- Universal's Cabana Bay Beach Resort
- DoubleTree by Hilton Hotel Orlando at SeaWorld
- Westgate Lakes Resort & Spa Universal Studios Area
- DoubleTree by Hilton at the Entrance to Universal Orlando
- Caribe Royale Orlando
- Hyatt Regency Orlando
- Hilton Vacation Club Grande Villas Orlando
Top Attractions in Lake Nona Medical City
- Hotels near Nemours Children's Hospital (0.64 mi)
- Hotels near VA Medical Center at Lake Nona (0.1 mi)
- Hotels near University of Central Florida College of Medicine (0.34 mi)
- Hotels near Sanford-Burnham Medical Research Institute (0.87 mi)
- Hotels near Walt Disney World® Resort (18.93 mi)
- Hotels near Universal Studios Florida (14.12 mi)
- Hotels near Disney SpringsTM (14.75 mi)
- Hotels near Universal Orlando Resort (13.79 mi)
- Hotels near Magic Kingdom® Park (18.93 mi)
- Hotels near Orange County Convention Center (12.48 mi)
- Hotels near Disney's Animal Kingdom® Theme Park (19.23 mi)
- Hotels near Epcot® (16.65 mi)
- Hotels near University of Central Florida (16.81 mi)
- Hotels near Universal’s Volcano Bay (13.68 mi)
- Hotels near Kia Center (13.58 mi)
- Hotels near Universal’s Islands of Adventure (13.94 mi)
- Hotels near ESPN Wide World of Sports Complex (17.24 mi)
- Hotels near Disney's Hollywood Studios® (17.37 mi)
- Hotels near Florida Mall (9.06 mi)
- Hotels near Orlando International Premium Outlets (12.97 mi)
Nearby Cities
- Kissimmee Hotels (9.6 mi)
- Lake Buena Vista Hotels (16.13 mi)
- Davenport Hotels (24.45 mi)
- Winter Garden Hotels (23.31 mi)
- Four Corners Hotels (21.85 mi)
- Celebration Hotels (15.96 mi)
- International Drive Hotels (12.37 mi)
- Winter Park Hotels (16.52 mi)
- Altamonte Springs Hotels (21.01 mi)
- Windermere Hotels (18.09 mi)
- Gulf Coast Hotels (777.55 mi)
- St. Cloud Hotels (18.15 mi)
Recommended cities for you
- Las Vegas Hotels
- New York Hotels
- Orlando Hotels
- Los Angeles Hotels
- Miami Hotels
- San Francisco Hotels
- New Orleans Hotels
- Chicago Hotels
- Fort Lauderdale Hotels
- Boston Hotels
- Honolulu Hotels
- San Diego Hotels
- Washington Hotels
- Toronto Hotels
- Anaheim Hotels
- Atlanta Hotels
- Nashville Hotels
- Seattle Hotels
- Phoenix Hotels
- Myrtle Beach Hotels
Car Rentals Near Lake Nona Medical City
- Car rentals in Kissimmee
- Car rentals in Lake Buena Vista
- Car rentals in Davenport
- Car rentals in Winter Garden
- Car rentals in Four Corners
- Car rentals in Celebration
- Car rentals in International Drive
- Car rentals in Winter Park
- Car rentals in Altamonte Springs
- Car rentals in Windermere
- Car rentals in Gulf Coast
- Car rentals in St. Cloud
- Car rentals in Oviedo
- Car rentals in Maitland
- Car rentals in Ocoee
- Car rentals in Disney's Boardwalk