Hotels NearClayton
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Featured Clayton Hotels

Clayton Plaza Hotel & Extended Stay
"I loved this hotel, especially for the cost per night. The breakfast buffet was great with tons of options, like a full-service restaurant. The front desk staff were amazing and the customer service was on point. They have a small laundry room and vending area, and everything is functional. The small ..."
Reviewed on Jun 12, 2026

Le Méridien St. Louis Clayton
"Dinning and pool areas were enjoyable."
Reviewed on Jun 2, 2026

The Ritz-Carlton, St. Louis
"We went on Memorial Day weekend which may have been why but there were so many weddings! (7) The car park was situated so that unless you walked outside and hiked the perimeter of the property you had to navigate through wedding guests to get to your car."
Reviewed on Jun 5, 2026

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
"The shower was almost non-existent, barely trickled out of the faucet no matter the adjustable head, which made it very difficult to get a shower. The bed was extremely firm, so if you have any back issues at all you may want to think twice about staying here. Also, it was the weekend and there was ..."
Reviewed on Jun 8, 2026

AC Hotel St. Louis Clayton
"Staff was excellent,rooftop bar super"
Reviewed on Jun 13, 2026

Hyatt Regency St. Louis at The Arch
"Extremely helpful and kind--thanks to Dominic helping with our luggage!"
Reviewed on Jun 13, 2026

Pear Tree Inn St. Louis Near Union Station
"So good"
Reviewed on Jun 13, 2026

Hollywood Casino & Hotel St. Louis
"People next to us was loud all night. Smelled like weed. Tried to get security up there. No one came in. Anniversary was ruined."
Reviewed on Jun 14, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
"We didn’t have working ac the 1st. Night then they switched our rooms and the bathtub didn’t work and they didn’t replenish our towels… disappointed"
Reviewed on Jun 13, 2026

Pear Tree Inn St. Louis Airport
"Clean room and coffee maker, spacious bathroom and comfy beds."
Reviewed on Jun 13, 2026

Drury Plaza Hotel St. Louis at the Arch
"I love the drury hotel but had an interior room this time and didn't like it. I like to be able to see outside."
Reviewed on Jun 14, 2026

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
"NA"
Reviewed on Jun 13, 2026
Hotels in Clayton
St. Louis is a city that has a lot going on, but you have your sights set on Clayton. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Clayton has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Clayton hotels that will do the trick.
A beautiful day in the neighborhood
As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Clayton underground. What’s a journey without a good story to go with it?
Beyond the block
We’re not talking about the Clayton city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Clayton cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:
- Hotwire Hot Rate: Snag some of the best hotels in Clayton at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
- Price: You have a price in mind, and we have solutions. Hotels start as low as $106
- Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.
Find the Clayton hotel you want, book it, and never look back. Because your great escape is ahead of you.
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More Hotel Options in Clayton
- Historic Hotels in Clayton
- Family Hotels in Clayton
- Hotels with a Pool in Clayton
- Hotel Wedding Venues in Clayton
- Hotels with Hot Tubs in Clayton
- Romantic Hotels in Clayton
- Luxury Hotels in Clayton
- Boutique Hotels in Clayton
- Resorts & Hotels with Spas in Clayton
- Hotels with an Indoor Pool in Clayton
Clayton Neighborhoods
Top Attractions in Clayton
- Hotels near Chapel of St. Timothy And St. Titus (0.71 mi)
- Hotels near St. Louis Union Station (6.35 mi)
- Hotels near Gateway Arch (7.59 mi)
- Hotels near Busch Stadium (7.18 mi)
- Hotels near St. Louis Zoo (1.86 mi)
- Hotels near Forest Park (2.49 mi)
- Hotels near Washington University in St. Louis (0.84 mi)
- Hotels near Hollywood Casino Amphitheatre (10.51 mi)
- Hotels near City Museum (6.66 mi)
- Hotels near Enterprise Center (6.62 mi)
- Hotels near Barnes Jewish Hospital (3.21 mi)
- Hotels near Dome at America’s Center (7.31 mi)
- Hotels near Mississippi River (76.74 mi)
- Hotels near Ameristar Casino St. Charles (12.3 mi)
- Hotels near America's Center Convention Complex (7.18 mi)
- Hotels near St. Louis University (4.93 mi)
- Hotels near Chaifetz Arena (5.2 mi)
- Hotels near St. Louis Aquarium at Union Station (6.35 mi)
- Hotels near Fox Theater (4.96 mi)
- Hotels near Horseshoe St. Louis Casino (7.55 mi)
Cities near Clayton
- St. Charles Hotels (13.73 mi)
- Maryland Heights Hotels (7.51 mi)
- Chesterfield Hotels (13.04 mi)
- O'Fallon Hotels (22.54 mi)
- Fenton Hotels (11.04 mi)
- St. Peters Hotels (19 mi)
- Fairview Heights Hotels (17.13 mi)
- O'Fallon Hotels (23.35 mi)
- Hazelwood Hotels (10.12 mi)
- Collinsville Hotels (18.31 mi)
- Eureka Hotels (19.05 mi)
- Alton Hotels (18.7 mi)
- Edwardsville Hotels (21.4 mi)
- Ozarks Hotels (156.82 mi)
- Kirkwood Hotels (6.06 mi)
- Bridgeton Hotels (9.81 mi)
- Richmond Heights Hotels (0.98 mi)
- Belleville Hotels (20.19 mi)
- Arnold Hotels (14.77 mi)
- East St. Louis Hotels (9.66 mi)
