Hotels NearClayton
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Featured Clayton Hotels

Clayton Plaza Hotel & Extended Stay
"Very nice well maintained older hotel with great updates to the rooms."
Reviewed on Jun 8, 2026

Le Méridien St. Louis Clayton
"Dinning and pool areas were enjoyable."
Reviewed on Jun 2, 2026

The Ritz-Carlton, St. Louis
"We went on Memorial Day weekend which may have been why but there were so many weddings! (7) The car park was situated so that unless you walked outside and hiked the perimeter of the property you had to navigate through wedding guests to get to your car."
Reviewed on Jun 5, 2026

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
"Room was not cleaned at all. Bathroom tub, toilet, and floors were absolutely filthy. For the price we paid for our stay, we were completely disappointed."
Reviewed on Jun 7, 2026

AC Hotel St. Louis Clayton
"I have stayed at this property multiple times and the entire staff during a recent visit were not interested in doing anything more than the bare minimum. We couldn't get one of our rooms cleaned the entire stay despite repeated requests. Valet attendants were difficult to communicate with and self ..."
Reviewed on Jun 6, 2026

Hyatt Regency St. Louis at The Arch
"The stay was excellent but when you are ready to leave getting your car is stressful we had to wait half-hour in line to retrieve our vehicle other than the stay was excellent"
Reviewed on Jun 7, 2026

Pear Tree Inn St. Louis Near Union Station
"Staff was great- very friendly and helpful. Location was very good as well, near to Union station with restaurants and activities. Hotel rooms and bathrooms need maintenance and work, paint falling off, pipes leaking in front of elevators on the 4th floor, outdoor had some litter around- in need ..."
Reviewed on Jun 7, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
"Great customer service could not be happier"
Reviewed on Jun 8, 2026

Pear Tree Inn St. Louis Airport
"The staff were very helpful and congenial. The free shuttle to the airport was helpful. The coffee offered in the lobby (bespoke brand) was fantastic! I’ll stay here again."
Reviewed on Jun 7, 2026

Drury Plaza Hotel St. Louis at the Arch
"Breakfast and happy hours were great. Loved the roof top deck, but wish we could have sat out at night. It was closed when the pool was closed. Location was perfect since we were in town to go to the Arch and also baseball games."
Reviewed on Jun 8, 2026

Live by Loews - St.Louis
"Location and it was really beautiful for the price."
Reviewed on Jun 6, 2026

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
"Great hotel that is walking distance to the Gateway Arch. The staff were so nice and friendly. We were so extremely happy they granted us extra time because our flight was at 410 pm - so they allowed a later checkout time. Very thankful to everyone we came in contact with - everyone was so ..."
Reviewed on Jun 7, 2026
Hotels in Clayton
St. Louis is a city that has a lot going on, but you have your sights set on Clayton. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Clayton has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Clayton hotels that will do the trick.
A beautiful day in the neighborhood
As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Clayton underground. What’s a journey without a good story to go with it?
Beyond the block
We’re not talking about the Clayton city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Clayton cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:
- Hotwire Hot Rate: Snag some of the best hotels in Clayton at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
- Price: You have a price in mind, and we have solutions. Hotels start as low as $106
- Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.
Find the Clayton hotel you want, book it, and never look back. Because your great escape is ahead of you.
- Top Hotels by Star Rating
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Hotels by Star Rating
More Hotel Options in Clayton
- Historic Hotels in Clayton
- Family Hotels in Clayton
- Hotels with a Pool in Clayton
- Hotel Wedding Venues in Clayton
- Hotels with Hot Tubs in Clayton
- Romantic Hotels in Clayton
- Luxury Hotels in Clayton
- Boutique Hotels in Clayton
- Resorts & Hotels with Spas in Clayton
- Hotels with an Indoor Pool in Clayton
Clayton Neighborhoods
Top Attractions in Clayton
- Hotels near Chapel of St. Timothy And St. Titus (0.71 mi)
- Hotels near Busch Stadium (7.18 mi)
- Hotels near St. Louis Union Station (6.35 mi)
- Hotels near Gateway Arch (7.59 mi)
- Hotels near St. Louis Zoo (1.86 mi)
- Hotels near Forest Park (2.49 mi)
- Hotels near Washington University in St. Louis (0.84 mi)
- Hotels near Dome at America’s Center (7.31 mi)
- Hotels near Enterprise Center (6.62 mi)
- Hotels near Barnes Jewish Hospital (3.21 mi)
- Hotels near City Museum (6.66 mi)
- Hotels near Mississippi River (76.74 mi)
- Hotels near Hollywood Casino Amphitheatre (10.51 mi)
- Hotels near America's Center Convention Complex (7.18 mi)
- Hotels near Ameristar Casino St. Charles (12.3 mi)
- Hotels near St. Louis University (4.93 mi)
- Hotels near Horseshoe St. Louis Casino (7.55 mi)
- Hotels near Anheuser-Busch Brewery (6.88 mi)
- Hotels near St Charles Convention Center (12.99 mi)
- Hotels near Grant's Farm (6.55 mi)
Cities near Clayton
- St. Charles Hotels (13.73 mi)
- Maryland Heights Hotels (7.51 mi)
- Chesterfield Hotels (13.04 mi)
- O'Fallon Hotels (22.54 mi)
- Fenton Hotels (11.04 mi)
- St. Peters Hotels (19 mi)
- O'Fallon Hotels (23.35 mi)
- Fairview Heights Hotels (17.13 mi)
- Alton Hotels (18.7 mi)
- Collinsville Hotels (18.31 mi)
- Belleville Hotels (20.19 mi)
- Eureka Hotels (19.05 mi)
- Hazelwood Hotels (10.12 mi)
- Kirkwood Hotels (6.06 mi)
- Edwardsville Hotels (21.4 mi)
- Ozarks Hotels (156.82 mi)
- Bridgeton Hotels (9.81 mi)
- Richmond Heights Hotels (0.98 mi)
- Arnold Hotels (14.77 mi)
- Valley Park Hotels (11.16 mi)
