Hotels NearClayton
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Featured Clayton Hotels

Clayton Plaza Hotel & Extended Stay
A very clean classy place. Staff were all friendly and helpful. They have a workout room, laundry room, etc... Pool closed and restaurant on limited hours due to remodeling but we enjoyed our stay there and were very pleased with everything.
Reviewed on Nov 17, 2025

AC Hotel St. Louis Clayton
Clean , modern rooms
Reviewed on Nov 10, 2025

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Very courteous staff. Room was clean. Breakfast area was clean and well-stocked. Little trouble with WiFi on first evening. Easy parking. Very convenient location.
Reviewed on Nov 16, 2025

Le Méridien St. Louis Clayton
Small rooms but beautiful lobby.
Reviewed on Oct 27, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
The room was clean and spacious. Hotel staff were nice and very accommodating given the issues we had with the valet service. While I understand the valet is a seperate entity, the hotel should revisit their relationship with thos vendor. They need to improve with more valets available each shift. ...
Reviewed on Nov 17, 2025

Forest Park Hotel by MDR
The property is right off of 44 with many fast food and gas stations nearby. It was clean and quiet. Perfect for my quick overnight stay.
Reviewed on Nov 16, 2025

Drury Plaza Hotel St. Louis at the Arch
Provided breakfast and dinner. Also three complimentary drinks at dinner!
Reviewed on Nov 14, 2025

Hyatt Regency St. Louis at The Arch
Nice hotel close to the arch. Ruth steakhouse is right inside hotel. Staff pleasant
Reviewed on Nov 15, 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Good breakfast, clean
Reviewed on Nov 15, 2025

21C Museum Hotel St Louis
Great vibes
Reviewed on Nov 14, 2025

Pear Tree Inn St. Louis Airport
Room was very clean. Bed is comfortable
Reviewed on Nov 15, 2025

Hollywood Casino & Hotel St. Louis
Room was a little dusty but nothing bad.
Reviewed on Nov 14, 2025
Hotels in Clayton
St. Louis is a city that has a lot going on, but you have your sights set on Clayton. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Clayton has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Clayton hotels that will do the trick.
A beautiful day in the neighborhood
As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Clayton underground. What’s a journey without a good story to go with it?
Beyond the block
We’re not talking about the Clayton city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Clayton cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:
- Hotwire Hot Rate: Snag some of the best hotels in Clayton at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
- Price: You have a price in mind, and we have solutions. Hotels start as low as $98
- Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.
Find the Clayton hotel you want, book it, and never look back. Because your great escape is ahead of you.
- Top Hotels by Star Rating
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- Popular Neighborhoods
- Hotels Near Top Attractions
- Nearby Cities
Hotels by Star Rating
More Hotel Options in Clayton
- Historic Hotels in Clayton
- Family Hotels in Clayton
- Hotels with a Pool in Clayton
- Hotel Wedding Venues in Clayton
- Hotels with Hot Tubs in Clayton
- Romantic Hotels in Clayton
- Luxury Hotels in Clayton
- Boutique Hotels in Clayton
- Resorts & Hotels with Spas in Clayton
- Hotels with an Indoor Pool in Clayton
Clayton Neighborhoods
Top Attractions in Clayton
- Hotels near Chapel of St. Timothy And St. Titus (0.71 mi)
- Hotels near St. Louis Union Station (6.35 mi)
- Hotels near Gateway Arch (7.59 mi)
- Hotels near St. Louis Zoo (1.86 mi)
- Hotels near Enterprise Center (6.62 mi)
- Hotels near Busch Stadium (7.18 mi)
- Hotels near Dome at America’s Center (7.31 mi)
- Hotels near Washington University in St. Louis (0.84 mi)
- Hotels near Barnes Jewish Hospital (3.21 mi)
- Hotels near City Museum (6.66 mi)
- Hotels near Forest Park (2.49 mi)
- Hotels near Ameristar Casino St. Charles (12.3 mi)
- Hotels near America's Center Convention Complex (7.18 mi)
- Hotels near Mississippi River (76.74 mi)
- Hotels near St. Louis University (4.93 mi)
- Hotels near St Charles Convention Center (12.99 mi)
- Hotels near Fox Theater (4.96 mi)
- Hotels near Hollywood Casino Amphitheatre (10.51 mi)
- Hotels near Horseshoe St. Louis Casino (7.55 mi)
- Hotels near Westport Plaza (7.79 mi)
Cities near Clayton
- St. Charles Hotels (13.73 mi)
- Chesterfield Hotels (13.04 mi)
- Maryland Heights Hotels (7.51 mi)
- O'Fallon Hotels (22.54 mi)
- Fairview Heights Hotels (17.13 mi)
- St. Peters Hotels (19 mi)
- O'Fallon Hotels (23.35 mi)
- Fenton Hotels (11.04 mi)
- Alton Hotels (18.7 mi)
- Collinsville Hotels (18.31 mi)
- Edwardsville Hotels (21.4 mi)
- Eureka Hotels (19.05 mi)
- Kirkwood Hotels (6.06 mi)
- Brentwood Hotels (2.21 mi)
- Arnold Hotels (14.77 mi)
- Bridgeton Hotels (9.81 mi)
- Belleville Hotels (20.19 mi)
- Richmond Heights Hotels (0.98 mi)
- Ozarks Hotels (156.82 mi)
- Webster Groves Hotels (3.9 mi)
