Hotels NearClayton
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Featured Clayton Hotels

Clayton Plaza Hotel & Extended Stay
Room comfortable and clean. Dtaff very polite, professional, and helpful.
Reviewed on Jan 25, 2026

The Ritz-Carlton, St. Louis
Very courteo
Reviewed on Jan 13, 2026

Le Méridien St. Louis Clayton
Nice
Reviewed on Jan 5, 2026

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
The breakfast was fresh. LOts of great options.. I do wish there were a few more meat choices and egg choices. BUt you have a great variety and very friendly kitchen help!! Also the bar had great Service and bartender was super nice.. A few more options and price lowered and it wouldve been perfect.. ...
Reviewed on Jan 12, 2026

AC Hotel St. Louis Clayton
My room was spotless and very well put together.
Reviewed on Jan 9, 2026

21C Museum Hotel St Louis
Staff was great!
Reviewed on Jan 25, 2026

Drury Plaza Hotel St. Louis at the Arch
Nice staff, clean rooms, dinner and breakfast for quests.
Reviewed on Jan 25, 2026

Hyatt Regency St. Louis at The Arch
Great location and vibe. I will definitely return
Reviewed on Jan 23, 2026

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Beautiful hotel with extremely friendly staff who were beyond kind and attentive
Reviewed on Jan 27, 2026

Live by Loews - St.Louis
Great check in staff... Parking valet attendant wonderful... Rooms clean, quiet and spacious!!! Highly recommend!!!
Reviewed on Jan 25, 2026

Home2 Suites by Hilton St. Louis Downtown
So clean wonderful staff great location so much fun best breakfast would do that again for sure!
Reviewed on Jan 20, 2026

Marriott St. Louis Grand
Large room, very clean, centrally located!
Reviewed on Jan 17, 2026
Hotels in Clayton
St. Louis is a city that has a lot going on, but you have your sights set on Clayton. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Clayton has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Clayton hotels that will do the trick.
A beautiful day in the neighborhood
As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Clayton underground. What’s a journey without a good story to go with it?
Beyond the block
We’re not talking about the Clayton city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Clayton cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:
- Hotwire Hot Rate: Snag some of the best hotels in Clayton at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
- Price: You have a price in mind, and we have solutions. Hotels start as low as $105
- Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.
Find the Clayton hotel you want, book it, and never look back. Because your great escape is ahead of you.
- Top Hotels by Star Rating
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- Popular Neighborhoods
- Hotels Near Top Attractions
- Nearby Cities
Hotels by Star Rating
More Hotel Options in Clayton
- Historic Hotels in Clayton
- Family Hotels in Clayton
- Hotels with a Pool in Clayton
- Hotel Wedding Venues in Clayton
- Hotels with Hot Tubs in Clayton
- Romantic Hotels in Clayton
- Luxury Hotels in Clayton
- Boutique Hotels in Clayton
- Resorts & Hotels with Spas in Clayton
- Hotels with an Indoor Pool in Clayton
Clayton Neighborhoods
Top Attractions in Clayton
- Hotels near Chapel of St. Timothy And St. Titus (0.71 mi)
- Hotels near St. Louis Union Station (6.35 mi)
- Hotels near Busch Stadium (7.18 mi)
- Hotels near Gateway Arch (7.59 mi)
- Hotels near St. Louis Zoo (1.86 mi)
- Hotels near Washington University in St. Louis (0.84 mi)
- Hotels near Enterprise Center (6.62 mi)
- Hotels near Barnes Jewish Hospital (3.21 mi)
- Hotels near America's Center Convention Complex (7.18 mi)
- Hotels near Dome at America’s Center (7.31 mi)
- Hotels near City Museum (6.66 mi)
- Hotels near Forest Park (2.49 mi)
- Hotels near Ameristar Casino St. Charles (12.3 mi)
- Hotels near St. Louis University (4.93 mi)
- Hotels near Mississippi River (76.74 mi)
- Hotels near Hollywood Casino Amphitheatre (10.51 mi)
- Hotels near Fox Theater (4.96 mi)
- Hotels near Westport Plaza (7.79 mi)
- Hotels near Horseshoe St. Louis Casino (7.55 mi)
- Hotels near St Charles Convention Center (12.99 mi)
Cities near Clayton
- St. Charles Hotels (13.73 mi)
- Maryland Heights Hotels (7.51 mi)
- O'Fallon Hotels (22.54 mi)
- Chesterfield Hotels (13.04 mi)
- St. Peters Hotels (19 mi)
- Fenton Hotels (11.04 mi)
- Eureka Hotels (19.05 mi)
- Ozarks Hotels (156.82 mi)
- Fairview Heights Hotels (17.13 mi)
- Hazelwood Hotels (10.12 mi)
- O'Fallon Hotels (23.35 mi)
- Edwardsville Hotels (21.4 mi)
- Florissant Hotels (10.13 mi)
- Arnold Hotels (14.77 mi)
- Collinsville Hotels (18.31 mi)
- Kirkwood Hotels (6.06 mi)
- Bridgeton Hotels (9.81 mi)
- Valley Park Hotels (11.16 mi)
- Belleville Hotels (20.19 mi)
- Richmond Heights Hotels (0.98 mi)
