Hotels NearClayton
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Featured Clayton Hotels

Clayton Plaza Hotel & Extended Stay
Excellent
Reviewed on Oct 24, 2025

AC Hotel St. Louis Clayton
They had an interesting bar at the top floor that unfortunately we couldn’t try
Reviewed on Oct 20, 2025

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Overall great experience, in a beautiful part of town. Very accessible to a lot of areas including dinning and shopping. Staff was very courteous and helpful!
Reviewed on Oct 18, 2025

Drury Plaza Hotel St. Louis at the Arch
It was close to everything we did
Reviewed on Oct 28, 2025

Hyatt Regency St. Louis at The Arch
Didn’t have a chance to eat the breakfast but otherwise a very good hotel. I liked the privacy of our room and the staff were all very friendly.
Reviewed on Oct 25, 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Good hotel
Reviewed on Oct 24, 2025

Renaissance St. Louis Airport Hotel
Staff was excellent
Reviewed on Oct 26, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Beautiful place to stay
Reviewed on Oct 24, 2025

Forest Park Hotel by MDR
Clean room and nice staff
Reviewed on Oct 23, 2025

Sonesta ES Suites St. Louis - Chesterfield
This place exceeded my expectations. The rooms were very clean. It was very spacious. More than enough TV’s. The beds were clean and comfortable. The check in process was super simple, and the gentleman was incredibly nice. I will definitely be coming back. I am so glad we chose to stay here!
Reviewed on Oct 20, 2025

21C Museum Hotel St Louis
The overall set up of the room was perfect. I loved everything; from the bed sheets, robes, huge bathtub and separate walk in shower. It felt cozy yet luxurious. The staff on the other hand were very pretentious. The lobby area is extremely loud and while checking in the staff spoke in a low tone ...
Reviewed on Oct 26, 2025

St. Louis Union Station Hotel, Curio Collection by Hilton
The hotel is amazing. All of the restaurants and attractions close by plus the light show done nightly on the hour was amazing.
Reviewed on Oct 20, 2025
Hotels in Clayton
St. Louis is a city that has a lot going on, but you have your sights set on Clayton. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Clayton has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Clayton hotels that will do the trick.
A beautiful day in the neighborhood
As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Clayton underground. What’s a journey without a good story to go with it?
Beyond the block
We’re not talking about the Clayton city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Clayton cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:
- Hotwire Hot Rate: Snag some of the best hotels in Clayton at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
- Price: You have a price in mind, and we have solutions. Hotels start as low as $93
- Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.
Find the Clayton hotel you want, book it, and never look back. Because your great escape is ahead of you.
- Top Hotels by Star Rating
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- Popular Neighborhoods
- Hotels Near Top Attractions
- Nearby Cities
Hotels by Star Rating
More Hotel Options in Clayton
- Historic Hotels in Clayton
- Family Hotels in Clayton
- Hotels with a Pool in Clayton
- Hotel Wedding Venues in Clayton
- Hotels with Hot Tubs in Clayton
- Romantic Hotels in Clayton
- Luxury Hotels in Clayton
- Boutique Hotels in Clayton
- Resorts & Hotels with Spas in Clayton
- Hotels with an Indoor Pool in Clayton
Clayton Neighborhoods
Top Attractions in Clayton
- Hotels near Chapel of St. Timothy And St. Titus (0.71 mi)
- Hotels near Busch Stadium (7.18 mi)
- Hotels near St. Louis Union Station (6.35 mi)
- Hotels near Gateway Arch (7.59 mi)
- Hotels near Washington University in St. Louis (0.84 mi)
- Hotels near St. Louis Zoo (1.86 mi)
- Hotels near Enterprise Center (6.62 mi)
- Hotels near Dome at America’s Center (7.31 mi)
- Hotels near City Museum (6.66 mi)
- Hotels near Forest Park (2.49 mi)
- Hotels near St. Louis University (4.93 mi)
- Hotels near Mississippi River (76.74 mi)
- Hotels near Hollywood Casino Amphitheatre (10.51 mi)
- Hotels near America's Center Convention Complex (7.18 mi)
- Hotels near Ameristar Casino St. Charles (12.3 mi)
- Hotels near Barnes Jewish Hospital (3.21 mi)
- Hotels near Fox Theater (4.96 mi)
- Hotels near Westport Plaza (7.79 mi)
- Hotels near Horseshoe St. Louis Casino (7.55 mi)
- Hotels near Hollywood Casino (11.47 mi)
Cities near Clayton
- St. Charles Hotels (13.73 mi)
- Maryland Heights Hotels (7.51 mi)
- Chesterfield Hotels (13.04 mi)
- O'Fallon Hotels (22.54 mi)
- Fairview Heights Hotels (17.13 mi)
- St. Peters Hotels (19 mi)
- O'Fallon Hotels (23.35 mi)
- Fenton Hotels (11.04 mi)
- Alton Hotels (18.7 mi)
- Brentwood Hotels (2.21 mi)
- Collinsville Hotels (18.31 mi)
- Edwardsville Hotels (21.4 mi)
- Eureka Hotels (19.05 mi)
- Bridgeton Hotels (9.81 mi)
- Ozarks Hotels (156.82 mi)
- Kirkwood Hotels (6.06 mi)
- Hazelwood Hotels (10.12 mi)
- Arnold Hotels (14.77 mi)
- Richmond Heights Hotels (0.98 mi)
- Belleville Hotels (20.19 mi)
