Adults Only Resorts & Hotels inDowntown San Francisco
Check Last Minute Downtown San Francisco Hotel Deals
Featured Downtown San Francisco Adults Only Resorts & Hotels
Hotels in Downtown San Francisco
San Francisco is a city that has a lot going on, but you have your sights set on Downtown San Francisco. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Downtown San Francisco has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Downtown San Francisco hotels that will do the trick.
A beautiful day in the neighborhood
As much as you like getting out there, it’s also good to know a part of San Francisco so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Downtown San Francisco underground. What’s a journey without a good story to go with it?
Beyond the block
We’re not talking about the Downtown San Francisco city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Downtown San Francisco cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:
- Hotwire Hot Rate: Snag some of the best hotels in Downtown San Francisco at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
- Price: You have a price in mind, and we have solutions. Hotels start as low as $117
- Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.
Find the Downtown San Francisco hotel you want, book it, and never look back. Because your great escape is ahead of you.
- Top Hotels
- Top Hotels by Star Rating
- More Hotel Types
- Popular Attractions
- Popular Neighborhoods
- Nearby Cities
Top Booked Hotels in Downtown San Francisco
- Holiday Inn Golden Gateway, an IHG Hotel
- Handlery Union Square Hotel
- Hilton San Francisco Financial District
- Club Quarters Hotel in San Francisco
- Hyatt Place San Francisco Downtown
- Hyatt Regency San Francisco
- The Westin St. Francis San Francisco on Union Square
- Hotel Nikko San Francisco
- Fairmont San Francisco
- King George Hotel
- Chancellor Hotel on Union Square
- The Marker Union Square San Francisco
- Hotel Spero at Union Square
- Palace Hotel, a Luxury Collection Hotel, San Francisco
More Hotel Options in Downtown San Francisco
- Historic Hotels in Downtown San Francisco
- Beach Hotels in Downtown San Francisco
- Winery Hotels in Downtown San Francisco
- Family Hotels in Downtown San Francisco
- Luxury Hotels in Downtown San Francisco
- Romantic Hotels in Downtown San Francisco
- Boutique Hotels in Downtown San Francisco
- Hotel Wedding Venues in Downtown San Francisco
- Pet-friendly Hotels in Downtown San Francisco
- Hotels with a Pool in Downtown San Francisco
- Hotels with Early Check-in in Downtown San Francisco
- Resorts & Hotels with Spas in Downtown San Francisco
- Apartment Hotel in Downtown San Francisco
- Hotels with Hot Tubs in Downtown San Francisco
- Hotels with Free Parking in Downtown San Francisco
- Hotels with smoking rooms in Downtown San Francisco
- Oceanfront Hotels in Downtown San Francisco
- Hotels with an Indoor Pool in Downtown San Francisco
- Gay friendly Hotels in Downtown San Francisco
- Casinos in Downtown San Francisco
Top Attractions in Downtown San Francisco
- Hotels near Oracle Park
- Hotels near Moscone Convention Center
- Hotels near Chase Center
- Hotels near Embarcadero Center
- Hotels near San Francisco Museum of Modern Art
- Hotels near Union Square
- Hotels near Ferry Building
- Hotels near Palace Hotel
- Hotels near Orpheum Theatre
- Hotels near Warfield Theatre
- Hotels near Bill Graham Civic Auditorium
- Hotels near San Francisco City Hall
- Hotels near Westin St Francis Hotel Glass Elevators
- Hotels near SF Masonic Auditorium
- Hotels near Van Ness Avenue
- Hotels near Asian Art Museum of San Francisco
- Hotels near Westfield San Francisco Centre
- Hotels near Grace Cathedral
- Hotels near Great American Music Hall
- Hotels near TransAmerica Pyramid
Downtown San Francisco Neighborhoods
- Union Square Hotels
- South of Market Hotels
- Nob Hill Hotels
- Financial District Hotels
- Western Addition Hotels
- Mission District Hotels
- Pacific Heights Hotels
- Chinatown Hotels
- Potrero Hill Hotels
- Embarcadero Hotels
- Civic Center Hotels
- Tenderloin Hotels
- South Beach Hotels
- Hayes Valley Hotels
- Jackson Square Hotels
Cities near Downtown San Francisco
- Half Moon Bay Hotels
- Berkeley Hotels
- South San Francisco Hotels
- Emeryville Hotels
- Sausalito Hotels
- Redwood City Hotels
- Walnut Creek Hotels
- Burlingame Hotels
- San Mateo Hotels
- Hayward Hotels
- Stinson Beach Hotels
- Pacifica Hotels
- Mill Valley Hotels
- Daly City Hotels
- San Rafael Hotels
- Alameda Hotels
- San Bruno Hotels
- Millbrae Hotels
- Northern California Hotels
- San Ramon Hotels
Car Rentals Near Downtown San Francisco
- Car rentals in Half Moon Bay
- Car rentals in Berkeley
- Car rentals in South San Francisco
- Car rentals in Emeryville
- Car rentals in Sausalito
- Car rentals in Redwood City
- Car rentals in Walnut Creek
- Car rentals in Burlingame
- Car rentals in San Mateo
- Car rentals in Hayward
- Car rentals in Stinson Beach
- Car rentals in Pacifica
- Car rentals in Mill Valley
- Car rentals in Daly City
- Car rentals in San Rafael
- Car rentals in Alameda