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Hotels in Mayfield

Choose from 1686 Mayfield Hotel Deals

Hilton Garden Inn Cleveland East/Mayfield Village

Hilton Garden Inn Cleveland East/Mayfield Village

3 out of 5
700 Beta Dr Mayfield OH
  • 24 min drive from Cleveland Clinic
Book a stay at this business-friendly hotel in Mayfield. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.4/10 Very Good! (1,002 reviews)
Clean room

Reviewed on Mar 2, 2026

Hilton Garden Inn Cleveland East/Mayfield Village
Holiday Inn Cleveland-Mayfield by IHG

Holiday Inn Cleveland-Mayfield by IHG

3 out of 5
780 Beta Dr Mayfield OH
  • 24 min drive from Cleveland Clinic
Book a stay at this business-friendly hotel in Mayfield. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9/10 Wonderful! (808 reviews)
Easy check in, room was spacious and comfortable (the beds were so comfy)! Would love to stay there again.

Reviewed on Mar 1, 2026

Holiday Inn Cleveland-Mayfield by IHG
Hotel Indigo Cleveland Downtown by IHG

Hotel Indigo Cleveland Downtown by IHG

3.5 out of 5
651 Huron Rd E Cleveland OH
  • 9 min drive from Cleveland Clinic
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.4/10 Very Good! (1,589 reviews)
Clean, comfortable, and reasonably priced! PLUS — right across the street from Rocket Arena and Jacob’s Field!!!

Reviewed on Mar 2, 2026

Hotel Indigo Cleveland Downtown by IHG
Hotel Cleveland, Autograph Collection

Hotel Cleveland, Autograph Collection

4 out of 5
24 Public Sq Cleveland OH
  • 10 min drive from Cleveland Clinic
Book a stay at this historic hotel in Cleveland. Enjoy breakfast (surcharge), a fitness center, and valet parking (surcharge). Our guests praise the helpful ...
9.2/10 Wonderful! (259 reviews)
We were there for a dance convention on a cold winter weekend. It was so nice to be able to have so many food choices within the hotel or at the attached mall. The hotel had many spots to be able to find a place to relax or meet up with people.

Reviewed on Mar 2, 2026

Hotel Cleveland, Autograph Collection
Hyatt Regency Cleveland At The Arcade

Hyatt Regency Cleveland At The Arcade

4 out of 5
420 Superior Ave E Cleveland OH
  • 9 min drive from Cleveland Clinic
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,124 reviews)
Yes

Reviewed on Mar 1, 2026

Hyatt Regency Cleveland At The Arcade
The Westin Cleveland Downtown

The Westin Cleveland Downtown

4 out of 5
777 Saint Clair Ave Ne Cleveland OH
  • 9 min drive from Cleveland Clinic
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (2,072 reviews)
The Westin offered an incredibly convenient location—everything I wanted to visit was within easy walking distance. My room was clean, spacious, and comfortable, and the bed was especially impressive. The valet team was consistently warm and welcoming, greeting me every time I entered the building, ...

Reviewed on Feb 28, 2026

The Westin Cleveland Downtown
Kimpton Schofield Hotel by IHG

Kimpton Schofield Hotel by IHG

4.5 out of 5
2000 East Ninth Street Cleveland OH
  • 9 min drive from Cleveland Clinic
Book a stay at this luxury hotel in Cleveland. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the restaurant and ...
8.8/10 Excellent! (1,007 reviews)
Amazing hotel in a great spot. Walking distance to rocket arena and great restaurants. Super clean and friendly staff

Reviewed on Mar 1, 2026

Kimpton Schofield Hotel by IHG
Holiday Inn Cleveland Clinic by IHG

Holiday Inn Cleveland Clinic by IHG

3 out of 5
8650 Euclid Ave Cleveland OH
  • 6 min walk from Cleveland Clinic
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,285 reviews)
Clean room, friendly staff. Good location for visit to Case Western.

Reviewed on Mar 2, 2026

Holiday Inn Cleveland Clinic by IHG
Wyndham Independence

Wyndham Independence

4 out of 5
6200 Quarry Lane Independence OH
  • 19 min drive from Cleveland Clinic
Book a stay at this business-friendly hotel in Independence. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Topgolf and Brandywine Falls ...
6.4/10 (1,013 reviews)
Yes, it was better than, I expected

Reviewed on Mar 2, 2026

Wyndham Independence
Drury Plaza Hotel Cleveland Downtown

Drury Plaza Hotel Cleveland Downtown

3 out of 5
1380 East 6th Street Cleveland OH
  • 9 min drive from Cleveland Clinic
Stay at this hotel in Cleveland. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (2,679 reviews)
Our room was clean and roomy with 2 double beds on the 6th floor. The pool and hot tub were clean and area was clean. The kids loved it! After a day of travel the complimentary dinner was certainly convenient and had several options. The complimentary breakfast also had great options! The valet parking ...

Reviewed on Mar 2, 2026

Drury Plaza Hotel Cleveland Downtown
Hilton Garden Inn Cleveland Downtown

Hilton Garden Inn Cleveland Downtown

3 out of 5
1100 Carnegie Ave Cleveland OH
  • 8 min drive from Cleveland Clinic
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff and ...
7.6/10 Good! (1,001 reviews)
Front desk was courteous didn’t use anything ekse

Reviewed on Feb 24, 2026

Hilton Garden Inn Cleveland Downtown
Crowne Plaza Cleveland at Playhouse Square by IHG

Crowne Plaza Cleveland at Playhouse Square by IHG

3.5 out of 5
1260 Euclid Ave Cleveland OH
  • 8 min drive from Cleveland Clinic
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the ...
9/10 Wonderful! (1,292 reviews)
Room was very nice and clean.Bed was comfortable.Staff was very friendly and pleasant.Would recommend.

Reviewed on Feb 23, 2026

Crowne Plaza Cleveland at Playhouse Square by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Mayfield

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Frequently Asked Questions About Mayfield hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Mayfield?

With over 1,686 hotels in Mayfield, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $54.

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Finding a cheap car rental deal in Mayfield is as easy as scoring cheap hotels in Mayfield. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.