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Hotels in Southeastern Indiana

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Choose from 1168 Southeastern Indiana Hotel Deals

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
  • 5 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms in our reviews. ...
7/10 Good! (2,809 reviews)
Everyone helped a lot and was very nice

Reviewed on Mar 1, 2026

Radisson Hotel Louisville North
Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

2.5 out of 5
411 W Spring Street New Albany IN
  • 12 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (771 reviews)
Great room, clean, and breakfast was really good with selection and quality!

Reviewed on Feb 28, 2026

Hampton Inn New Albany Louisville West
Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

3 out of 5
4900 Water Tower Road Jeffersonville IN
  • 16 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free parking, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
9.6/10 Exceptional! (450 reviews)
Would definitely stay here again! Coffee was good (minus a good bit of grounds at the bottom of my cup), air worked great for a warm February weekend, and the staff was very friendly. Be careful with aerosol deodorant; stayed in a lot of hotels but my husband's deo set off our room's fire alarm. ...

Reviewed on Mar 2, 2026

Hilton Garden Inn Jeffersonville Louisville North
Hampton Inn Louisville-North/Clarksville

Hampton Inn Louisville-North/Clarksville

2.5 out of 5
1501 Broadway Clarksville IN
  • 11 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Hampton Inn Louisville-North/Clarksville
Comfort Inn & Suites Clarksville - Louisville North

Comfort Inn & Suites Clarksville - Louisville North

2.5 out of 5
1485 Broadway St Clarksville IN
  • 11 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,002 reviews)
Clean lobby and breakfast area. Room was also clean.

Reviewed on Mar 1, 2026

Comfort Inn & Suites Clarksville - Louisville North
Motel 6 Jeffersonville, In - Louisville

Motel 6 Jeffersonville, In - Louisville

2 out of 5
2012 Hospitality Way Clarksville IN
  • 7 min drive from KFC Yum Center
Stay at this motel in Clarksville. Enjoy free parking, a 24-hour front desk, and daily housekeeping. Our guests praise the clean rooms in our reviews. Popular ...
6/10 (390 reviews)
Clean, and comfortable. Great price

Reviewed on Mar 1, 2026

Motel 6 Jeffersonville, In - Louisville
Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North

2.5 out of 5
360 Triangle Dr Sellersburg IN
  • 23 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Sellersburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,002 reviews)
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Reviewed on Mar 1, 2026

Ramada by Wyndham Sellersburg/Louisville North
Sheraton Louisville Riverside by Marriott

Sheraton Louisville Riverside by Marriott

3.5 out of 5
700 West Riverside Drive Jeffersonville IN
  • 18 min walk from KFC Yum Center
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free WiFi, free parking, and 3 bars/lounges. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,002 reviews)
Hotel was nice and clean. Good location. Pool and hot tub were nice. Only complaint: if you are going to advertise three restaurants onsite, there should be three restaurants. Change your description profile. The El Nopal was excellent.

Reviewed on Mar 2, 2026

Sheraton Louisville Riverside by Marriott
Holiday Inn Express & Suites Scottsburg by IHG

Holiday Inn Express & Suites Scottsburg by IHG

2.5 out of 5
200 S Beechwood Ave Scottsburg IN
  • 1 hour drive from KFC Yum Center
Book a stay at this business-friendly hotel in Scottsburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (678 reviews)
This is a great stop along I-65. The staff is very friendly and helpful, the hotel is clean, and the breakfast and coffee is good.

Reviewed on Feb 22, 2026

Holiday Inn Express & Suites Scottsburg by IHG
Big Splash Adventure Indoor Water Park & Resort

Big Splash Adventure Indoor Water Park & Resort

3.5 out of 5
8505 W State Road 56 French Lick IN
  • 2 hours drive from KFC Yum Center
Book a stay at this family-friendly resort in French Lick. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions French Lick Scenic Railway and ...
7.6/10 Good! (189 reviews)
Great service

Reviewed on Jan 27, 2026

Big Splash Adventure Indoor Water Park & Resort
TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North

3 out of 5
301 West Maple Street Jeffersonville IN
  • 23 min walk from KFC Yum Center
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and ...
9.2/10 Wonderful! (661 reviews)
Large, clean rooms and staff was exceptional!

Reviewed on Mar 1, 2026

TownePlace Suites by Marriott Louisville North
Candlewood Suites Louisville North by IHG

Candlewood Suites Louisville North by IHG

2.5 out of 5
1419 Bales Lane Clarksville IN
  • 12 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.4/10 Very Good! (408 reviews)
Suite was spacious and very clean. Staff extremely courteous and helpful. Would love to stay here again.

Reviewed on Mar 1, 2026

Candlewood Suites Louisville North by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southeastern Indiana

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southeastern Indiana.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southeastern Indiana’s 1,168 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $53. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southeastern Indiana hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southeastern Indiana. No matter your reason for visiting Southeastern Indiana, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southeastern Indiana hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southeastern Indiana for as low as $53.

How many hotels are there in Southeastern Indiana?

With over 1,168 hotels in Southeastern Indiana, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $53.

How to find cheap car rentals in Southeastern Indiana?

Finding a cheap car rental deal in Southeastern Indiana is as easy as scoring cheap hotels in Southeastern Indiana. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.