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Hotels in Southeastern Indiana

Choose from 1140 Southeastern Indiana Hotel Deals

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
  • 5 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms in our reviews. ...
7/10 Good! (2,959 reviews)
Didn’t eat at hotel.

Reviewed on Apr 13, 2026

Radisson Hotel Louisville North
Derby Hotel & Suites

Derby Hotel & Suites

2 out of 5
505 K Marriot Dr Clarksville IN
  • 5 min drive from KFC Yum Center
Stay at this hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Louisville Slugger Museum and KFC Yum Center are located ...
5.4/10 (20 reviews)
Shower was dirty and bed was stained. Worth it for the price though

Reviewed on Apr 12, 2026

Derby Hotel & Suites
Motel 6 Jeffersonville, In - Louisville

Motel 6 Jeffersonville, In - Louisville

2 out of 5
2012 Hospitality Way Clarksville IN
  • 7 min drive from KFC Yum Center
Stay at this motel in Clarksville. Enjoy free parking, a 24-hour front desk, and daily housekeeping. Our guests praise the clean rooms in our reviews. Popular ...
6.2/10 (426 reviews)
Decent stay

Reviewed on Apr 12, 2026

Motel 6 Jeffersonville, In - Louisville
Big Splash Adventure Indoor Water Park & Resort

Big Splash Adventure Indoor Water Park & Resort

3.5 out of 5
8505 W State Road 56 French Lick IN
  • 2 hours drive from KFC Yum Center
Book a stay at this family-friendly resort in French Lick. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions French Lick Scenic Railway and ...
7.6/10 Good! (190 reviews)
The staff was wonderful but the rooms are outdated there was rust everywhere. The water was so cold u could only be in it for an hour. It was definitely much smaller then expected and the rooms dont come with the water park access u have to buy thise separately. The food was all microwave food except ...

Reviewed on Mar 18, 2026

Big Splash Adventure Indoor Water Park & Resort
Candlewood Suites Louisville North by IHG

Candlewood Suites Louisville North by IHG

2.5 out of 5
1419 Bales Lane Clarksville IN
  • 12 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.4/10 Very Good! (438 reviews)
Our room was sold to someone else, we had 6 people in a room for 4. There were several strands of hair in the shower. The pool was closed due to chemicals and there was no breakfast or coffee. I can do much better for $150 elsewhere. Will not stay here again.

Reviewed on Apr 6, 2026

Candlewood Suites Louisville North by IHG
Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

3 out of 5
4900 Water Tower Road Jeffersonville IN
  • 16 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free parking, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
9.6/10 Exceptional! (471 reviews)
Had hot water issues and waiting for discount on stay through Expedia. The room, staff, and building were all very good. Would recommend as long as the fix the hot water issue.

Reviewed on Apr 12, 2026

Hilton Garden Inn Jeffersonville Louisville North
Comfort Inn & Suites Clarksville - Louisville North

Comfort Inn & Suites Clarksville - Louisville North

2.5 out of 5
1485 Broadway St Clarksville IN
  • 11 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,010 reviews)
Everything was good and the people were friendly and I enjoyed the entire 10 day stay thank you

Reviewed on Apr 10, 2026

Comfort Inn & Suites Clarksville - Louisville North
Best Western Plus French Lick

Best Western Plus French Lick

2.5 out of 5
613 S Arnold F Habig Boulevard French Lick IN
  • 2 hours drive from KFC Yum Center
Stay at this hotel in French Lick. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,005 reviews)
Would have been great to be able to get tv to work as kept saying couldn’t locate signal during March Madness!

Reviewed on Apr 11, 2026

Best Western Plus French Lick
The Villas at French Lick Springs

The Villas at French Lick Springs

3 out of 5
8718 W State Road 56 French Lick IN
  • 2 hours drive from KFC Yum Center
Stay at this condo in French Lick. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (307 reviews)
It lived up to the advertisement. We enjoyed the little town Larry Bird’s friend’s restaurant was a big hit with our family.

Reviewed on Apr 13, 2026

The Villas at French Lick Springs
Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

2.5 out of 5
411 W Spring Street New Albany IN
  • 12 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (784 reviews)
Quick, checkin, very friendly staff, and clean. Not enough toilet paper in room or towels for stay. Breakfast variety was ok, but wish there was a better variety.

Reviewed on Apr 6, 2026

Hampton Inn New Albany Louisville West
TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North

3 out of 5
301 West Maple Street Jeffersonville IN
  • 23 min walk from KFC Yum Center
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and ...
9.2/10 Wonderful! (674 reviews)
Staff was not friendly or helpful, the place was not very clean! There were a pee spots on the toilet and the bathroom floor was disgusting!

Reviewed on Apr 12, 2026

TownePlace Suites by Marriott Louisville North
Travelodge by Wyndham Sellersburg / Louisville North

Travelodge by Wyndham Sellersburg / Louisville North

2 out of 5
7618 Old State Road 60 Sellersburg IN
  • 20 min drive from KFC Yum Center
Stay at this motel in Sellersburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (714 reviews)
2nd time staying. Will stay again

Reviewed on Apr 12, 2026

Travelodge by Wyndham Sellersburg / Louisville North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southeastern Indiana

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southeastern Indiana.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southeastern Indiana’s 1,140 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $56. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southeastern Indiana hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southeastern Indiana. No matter your reason for visiting Southeastern Indiana, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southeastern Indiana hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southeastern Indiana for as low as $56.

How many hotels are there in Southeastern Indiana?

With over 1,140 hotels in Southeastern Indiana, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $56.

How to find cheap car rentals in Southeastern Indiana?

Finding a cheap car rental deal in Southeastern Indiana is as easy as scoring cheap hotels in Southeastern Indiana. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.