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4 Star Hotels in Mission Valley

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Featured 4 Star Mission Valley Hotels

San Diego Marriott La Jolla
4 out of 5
Fully refundableReserve now, pay when you stay
  • 19 min drive from Hotel Circle
The price is $162 per night from Nov 23 to Nov 24
$162
includes taxes & fees
Nov 23 - Nov 24
Book a stay at this business-friendly hotel in La Jolla. Enjoy breakfast (surcharge), a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
San Diego Marriott La Jolla
DoubleTree by Hilton Hotel San Diego - Mission Valley
4 out of 5
Fully refundableReserve now, pay when you stay
  • 14 min walk from Hotel Circle
The price is $162 per night from Nov 24 to Nov 25
$162
includes taxes & fees
Nov 24 - Nov 25
Book a stay at this business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful ...
DoubleTree by Hilton Hotel San Diego - Mission Valley
Wyndham San Diego Bayside
4 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min drive from Hotel Circle
The price is $162 per night from Nov 26 to Nov 27
$162
includes taxes & fees
Nov 26 - Nov 27
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
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Hyatt Regency Mission Bay Spa and Marina
4 out of 5
Fully refundableReserve now, pay when you stay
  • 21 min walk from Hotel Circle
The price is $215 per night from Dec 17 to Dec 18
$215
includes taxes & fees
Dec 17 - Dec 18
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Hyatt Regency Mission Bay Spa and Marina
Hard Rock Hotel San Diego
4 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min drive from Hotel Circle
The price is $267 per night from Nov 24 to Nov 25
$267
includes taxes & fees
Nov 24 - Nov 25
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our ...
Hard Rock Hotel San Diego
Manchester Grand Hyatt San Diego
4 out of 5
Fully refundableReserve now, pay when you stay
  • 8 min drive from Hotel Circle
The price is $238 per night from Nov 25 to Nov 26
$238
includes taxes & fees
Nov 25 - Nov 26
Book a stay at this eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
Manchester Grand Hyatt San Diego
Sheraton San Diego Hotel and Marina
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from Hotel Circle
The price is $169 per night from Nov 24 to Nov 25
$169
includes taxes & fees
Nov 24 - Nov 25
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 6 restaurants, and a marina. Our guests praise the pool and the restaurant in ...
Sheraton San Diego Hotel and Marina
Palihotel San Diego
4 out of 5
Fully refundableReserve now, pay when you stay
  • 8 min drive from Hotel Circle
The price is $152 per night from Dec 17 to Dec 18
$152
includes taxes & fees
Dec 17 - Dec 18
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in ...
Palihotel San Diego
Marriott Marquis San Diego Marina
4 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min drive from Hotel Circle
The price is $217 per night from Nov 26 to Nov 27
$217
includes taxes & fees
Nov 26 - Nov 27
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff in ...
Marriott Marquis San Diego Marina
Town and Country San Diego
4 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min walk from Hotel Circle
The price is $235 per night from Nov 18 to Nov 19
$235
includes taxes & fees
Nov 18 - Nov 19
Book a stay at this golf hotel in San Diego. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff in our reviews. ...
Town and Country San Diego
Embassy Suites by Hilton San Diego Bay Downtown
4 out of 5
Fully refundableReserve now, pay when you stay
  • 8 min drive from Hotel Circle
The price is $245 per night from Nov 24 to Nov 25
$245
includes taxes & fees
Nov 24 - Nov 25
Book a stay at this family-friendly hotel in San Diego. Enjoy room service, a fitness center, and WiFi (surcharge). Our guests praise the breakfast and the helpful ...
Embassy Suites by Hilton San Diego Bay Downtown
Paradise Point Resort & Spa
4 out of 5
Fully refundableReserve now, pay when you stay
  • 28 min walk from Hotel Circle
The price is $276 per night from Nov 19 to Nov 20
$276
includes taxes & fees
Nov 19 - Nov 20
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Paradise Point Resort & Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-Star Hotels in Mission Valley

If you're ready to live the good life, but not break the bank, it's time to look into a 4-star hotel in Mission Valley for your next vacation. You'll get all the perks you've been dreaming of (and then some) at a rate within your means. Sprawl out on high thread-count sheets, work on your tan by the scenic pool, indulge at a world-class restaurant, take a break from it all at the in-house spa ... All this and more is at your beck and call at Mission Valley 4-star hotels.

The 4 stars are aligned

So what's the star rating all about? Here's how it works: A hotel's star rating doesn't have much to do with the price of your room, and more to do with the glowing amenities. 4-star hotels in Mission Valley, San Diego, and everywhere else, often have all those fancy extras that make you go "Oh," "Wow," and "YES!" Think amenities like opulent bedding, sophisticated electronics, personalized concierge service, and cafes that make dining in a meal for the books.

Written in the stars

You know there are as many cool spots, divey lounges, and memory-making music venues as there are stars in the sky. But you'll need the funds to check them all off. That's why we give you the chance to save up to 60% with the Hotwire Hot Rate. You can book Mission Valley 4-star hotels and still have enough spending money to paint the town red. We have so many awesome options for your stay that we thought we'd to make it a bit easier to find the right hotel. Filter the best 4-star hotels in Mission Valley by:

  • Hotwire Hot Rate: With so many amazing hotels to choose from, we'll grab you a sweet deal on a room by telling you your hotel name after you book. Wishing on 4 stars? Not necessary.
  • Price: With prices as low as $152, we know you'll find a cheap 4-star hotel in Mission Valley that won't break the bank.
  • Amenities: What makes up your vacation wish list? Heated pool? Full-service spa? 24-hour room service? Find a hotel that'll send you over the moon.

You deserve the finer things. Perks galore and the sweetest spot to recharge in Mission Valley without blowing all of your fun money. When you book a Hotwire Hot Rate, you score that stellar Mission Valley 4-star hotel and have cash left to do everything you want on your superstar vacay. Hotwire has 8,322 Mission Valley hotels waiting for you, but the most popular rooms aren't available long so book your room today.