Search for Cheap Deals on
Hotels in Depew

Check Last Minute Depew Hotel Deals

Tonight Feb 2 - Feb 3Next weekend Feb 7 - Feb 9

Choose from 831 Depew Hotel Deals

Buffalo Airport Hotel
Buffalo Airport Hotel
3 out of 5
4600 Genesee St, Buffalo, NY
  • 13 min drive from University At Buffalo - North Campus
The price is $102 per night from Feb 3 to Feb 4
$102
includes taxes & fees
Feb 3 - Feb 4
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the bar ...
8/10 Very Good! (2,353 reviews)
"Good"

Reviewed on Jan 31, 2025

Buffalo Airport Hotel
M Hotel Buffalo
M Hotel Buffalo
3.5 out of 5
2040 Walden Ave, Buffalo, NY
  • 16 min drive from University At Buffalo - North Campus
The price is $130 per night from Feb 3 to Feb 4
$130
includes taxes & fees
Feb 3 - Feb 4
Stay at this 3.5-star business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff ...
7/10 Good! (1,219 reviews)
"Very nice place, very polite staff."

Reviewed on Jan 27, 2025

M Hotel Buffalo
Sleep Inn & Suites Buffalo Airport
Sleep Inn & Suites Buffalo Airport
2.5 out of 5
100 Holtz Dr, Buffalo, NY
  • 12 min drive from University At Buffalo - North Campus
The price is $91 per night from Feb 18 to Feb 19
$91
includes taxes & fees
Feb 18 - Feb 19
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,478 reviews)
"Good"

Reviewed on Jan 31, 2025

Sleep Inn & Suites Buffalo Airport
Comfort Inn & Suites Buffalo Airport
Comfort Inn & Suites Buffalo Airport
3 out of 5
4345 Genesee St, Buffalo, NY
  • 13 min drive from University At Buffalo - North Campus
The price is $96 per night from Feb 16 to Feb 17
$96
includes taxes & fees
Feb 16 - Feb 17
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (986 reviews)
"Close to the airport, nice, clean rooms at a reasonable price. My go to stay when flying out of Buffalo"

Reviewed on Jan 31, 2025

Comfort Inn & Suites Buffalo Airport
La Quinta Inn & Suites by Wyndham Buffalo Amherst
La Quinta Inn & Suites by Wyndham Buffalo Amherst
2.5 out of 5
145 Innkeepers Lane, Buffalo, NY
  • 24 min walk from University At Buffalo - North Campus
The price is $90 per night from Feb 9 to Feb 10
$90
includes taxes & fees
Feb 9 - Feb 10
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,711 reviews)
"Very clean suite and friendly staff. There are many dining options in the area, though you’ll probably want a car. Would definitely stay here again when I’m in the area."

Reviewed on Jan 31, 2025

La Quinta Inn & Suites by Wyndham Buffalo Amherst
Wyndham Garden Buffalo Downtown
Wyndham Garden Buffalo Downtown
3 out of 5
125 High St, Buffalo, NY
  • 18 min drive from University At Buffalo - North Campus
The price is $150 per night from Feb 9 to Feb 10
$150
includes taxes & fees
Feb 9 - Feb 10
Stay at this 3-star business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,314 reviews)
"We liked the location by the hospital, valet parking, hospitality shuttle, clean room, comfortable bed. I would have given a higher rating if greeted with enthusiasm at check in. Front desk did offer food delivery option's later after we revisited the front desk."

Reviewed on Jan 27, 2025

Wyndham Garden Buffalo Downtown
Garden Place Hotel
Garden Place Hotel
3.5 out of 5
6615 Transit Road, Buffalo, NY
  • 12 min drive from University At Buffalo - North Campus
The price is $90 per night from Feb 3 to Feb 4
$90
includes taxes & fees
Feb 3 - Feb 4
Stay at this 3.5-star business-friendly hotel in Buffalo. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.6/10 Good! (1,603 reviews)
"My sweet was wonderful. It was the best in the place"

Reviewed on Feb 1, 2025

Garden Place Hotel
Curtiss Hotel, Ascend Hotel Collection
Curtiss Hotel, Ascend Hotel Collection
5 out of 5
210 Franklin St, Buffalo, NY
  • 20 min drive from University At Buffalo - North Campus
The price is $214 per night from Feb 20 to Feb 21
$214
includes taxes & fees
Feb 20 - Feb 21
Stay at this 5-star luxury hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the bar and the helpful staff in our reviews. ...
9/10 Wonderful! (1,007 reviews)
"great"

Reviewed on Jan 31, 2025

Curtiss Hotel, Ascend Hotel Collection
Holiday Inn Express Cheektowaga North East, an IHG Hotel
Holiday Inn Express Cheektowaga North East, an IHG Hotel
2.5 out of 5
83 Anderson Rd, Buffalo, NY
  • 16 min drive from University At Buffalo - North Campus
The price is $118 per night from Feb 10 to Feb 11
$118
includes taxes & fees
Feb 10 - Feb 11
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,003 reviews)
"Everything was as it should be. Clean updated room. Clean pool. Good breakfast. Ample parking. Close to all of the stores. Great stay!"

Reviewed on Jan 30, 2025

Holiday Inn Express Cheektowaga North East, an IHG Hotel
Hyatt Place Buffalo/Amherst
Hyatt Place Buffalo/Amherst
3 out of 5
5020 Main Street, Buffalo, NY
  • 7 min drive from University At Buffalo - North Campus
The price is $135 per night from Feb 23 to Feb 24
$135
includes taxes & fees
Feb 23 - Feb 24
Stay at this 3-star business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9/10 Wonderful! (1,007 reviews)
A very satisfying stay
"Despite the bad weather (snow, wind) the hotel reception was clean and welcoming from the evening we arrived until the morning departure. Everything, every equipment worked well. The breakfast buffet was very good."

Reviewed on Jan 30, 2025

Hyatt Place Buffalo/Amherst
Hyatt Regency Buffalo / Hotel and Conference Center
Hyatt Regency Buffalo / Hotel and Conference Center
3.5 out of 5
Two Fountain Plaza, Buffalo, NY
  • 20 min drive from University At Buffalo - North Campus
The price is $163 per night from Feb 17 to Feb 18
$163
includes taxes & fees
Feb 17 - Feb 18
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
7.8/10 Good! (1,289 reviews)
"N/A"

Reviewed on Jan 28, 2025

Hyatt Regency Buffalo / Hotel and Conference Center
La Quinta Inn by Wyndham Buffalo Airport
La Quinta Inn by Wyndham Buffalo Airport
2.5 out of 5
6619 Transit Rd, Buffalo, NY
  • 12 min drive from University At Buffalo - North Campus
The price is $81 per night from Feb 9 to Feb 10
$81
includes taxes & fees
Feb 9 - Feb 10
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.6/10 Good! (1,104 reviews)
"Easy check in process"

Reviewed on Jan 22, 2025

La Quinta Inn by Wyndham Buffalo Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Depew

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Depew hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Depew.

Choosing the right hotel in New York has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Depew’s 831 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $81. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Depew hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Depew. No matter your reason for visiting Depew, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Depew hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Depew for as low as $81.

How many hotels are there in Depew?

With over 831 hotels in Depew, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $81.

How to find cheap car rentals in Depew?

Finding a cheap car rental deal in Depew is as easy as scoring cheap hotels in Depew. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.