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Featured 5 Star Otay Mesa Hotels
Fully refundableReserve now, pay when you stay
The price is $276 per night from May 26 to May 27
$276
per night
May 26 - May 27
Stay at this 5-star luxury hotel in San Diego. Enjoy free WiFi, 3 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. ...
Fully refundableReserve now, pay when you stay
The price is $284 per night from May 26 to May 27
$284
per night
May 26 - May 27
Stay at this business-friendly hotel in San Diego. Enjoy breakfast, WiFi, and 24-hour room service. Our guests praise the helpful staff in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular Otay Mesa Hotels
- Manchester Grand Hyatt San Diego
- Wyndham San Diego Bayside
- Wyndham Garden San Diego Near SeaWorld
- The Dana on Mission Bay
- San Diego Mission Bay Resort
- Paradise Point Resort & Spa
- Bahia Resort Hotel
- Hard Rock Hotel San Diego
- Hyatt Regency Mission Bay Spa and Marina
- Hilton San Diego Bayfront
- Best Western Seven Seas
Top Attractions in Otay Mesa
- Hotels near San Diego Zoo (15.96 mi)
- Hotels near Mission Bay (21.06 mi)
- Hotels near San Diego Convention Center (14.93 mi)
- Hotels near Mission Beach (21.83 mi)
- Hotels near San Ysidro Border Crossing (3.44 mi)
- Hotels near Balboa Park (15.52 mi)
- Hotels near Hotel Circle (18.15 mi)
- Hotels near Petco Park (14.77 mi)
- Hotels near San Diego State University (15.83 mi)
- Hotels near Naval Base San Diego (11.88 mi)
- Hotels near USS Midway Museum (15.84 mi)
- Hotels near Marine Corps Recruit Depot (18.04 mi)
- Hotels near Mission Beach Boardwalk (21.43 mi)
- Hotels near University of San Diego (19.36 mi)
- Hotels near Port of San Diego (15.92 mi)
- Hotels near Hotel del Coronado (14.54 mi)
- Hotels near B Street Cruise Ship Terminal (15.99 mi)
- Hotels near Naval Base Coronado (16.63 mi)
- Hotels near Coronado Beach (15.09 mi)
- Hotels near Las Americas Premium Outlets (4.1 mi)
Nearby Cities
- San Diego Hotels (15.34 mi)
- Rosarito Hotels (14.31 mi)
- Coronado Hotels (14.99 mi)
- Playas de Rosarito Hotels (21.71 mi)
- Chula Vista Hotels (8.51 mi)
- Coronado Island Hotels (16.04 mi)
- El Cajon Hotels (16.26 mi)
- Southern California Hotels (91.04 mi)
- National City Hotels (10.98 mi)
- Imperial Beach Hotels (8.3 mi)
- La Mesa Hotels (14.67 mi)
- San Ysidro Hotels (4.08 mi)
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Car Rentals Near Otay Mesa
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