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Featured Otay Mesa Hotels with a Pool
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2296 Niels Bohr Ct San Diego CA
Fully refundable
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Quality Suites San Diego Otay Mesa
2351 Otay Center Dr San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Otay Mesa
- Historic Hotels in Otay Mesa
- Hotels with Free Parking in Otay Mesa
- Beach Hotels in Otay Mesa
- Family Hotels in Otay Mesa
- Winery Hotels in Otay Mesa
- Hotels with Hot Tubs in Otay Mesa
- Casinos in Otay Mesa
- Resorts & Hotels with Spas in Otay Mesa
- Hotels with smoking rooms in Otay Mesa
- Luxury Hotels in Otay Mesa
Top Points of Interests in Otay Mesa
- Hotels near Cross Border Xpress
- Hotels near San Diego Zoo
- Hotels near San Diego Convention Center
- Hotels near Mission Bay
- Hotels near San Ysidro Border Crossing
- Hotels near Balboa Park
- Hotels near Port of San Diego
- Hotels near Petco Park
- Hotels near Hotel Circle
- Hotels near Mission Beach
- Hotels near Marine Corps Recruit Depot
- Hotels near Naval Base San Diego
- Hotels near USS Midway Museum
- Hotels near Hotel del Coronado
- Hotels near Las Americas Premium Outlets
- Hotels near Coronado Beach
- Hotels near University of San Diego
- Hotels near Seaport Village
- Hotels near San Diego State University
- Hotels near B Street Cruise Ship Terminal
Cities near Otay Mesa
- San Diego Hotels (15.34 mi)
- Chula Vista Hotels (8.51 mi)
- Coronado Hotels (14.99 mi)
- Playas de Rosarito Hotels (21.71 mi)
- Rosarito Hotels (14.31 mi)
- El Cajon Hotels (16.26 mi)
- Coronado Island Hotels (16.04 mi)
- National City Hotels (10.98 mi)
- Southern California Hotels (91.04 mi)
- La Mesa Hotels (14.67 mi)
- San Ysidro Hotels (4.08 mi)
- Imperial Beach Hotels (8.3 mi)
- Alpine Hotels (22.51 mi)
- Tecate Hotels (19.72 mi)
- Santee Hotels (19.26 mi)
- Spring Valley Hotels (12.88 mi)
- Lakeside Hotels (20.78 mi)
- Bonita Hotels (7.71 mi)
- Jamul Hotels (12.26 mi)
- Lemon Grove Hotels (13.08 mi)
Most Booked Hotels in Otay Mesa
- Hotel del Coronado, Curio Collection by Hilton
- Hilton San Diego Mission Valley
- Bay Club Hotel & Marina
- Hampton Inn & Suites by Hilton San Diego SeaWorld
- Hard Rock Hotel San Diego
- Courtyard by Marriott San Diego Downtown Little Italy
- The DEXTRO Little Italy, BW Premier Collection
- Comfort Inn Sea World Area
- Wyndham San Diego Bayside
- Pendry San Diego
- DoubleTree by Hilton Hotel San Diego - Mission Valley
- Comfort Inn San Diego Airport At The Harbor
- The Dana on Mission Bay
- Wyndham Garden San Diego Near SeaWorld
- Best Western Plus Marina Gateway Hotel