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Featured Otay Mesa Historic Hotels
Quality Suites San Diego Otay Mesa
2351 Otay Center Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel
2296 Niels Bohr Ct, San Diego, CA
Fully refundable
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Otay Mesa
- Hotels with a Pool in Otay Mesa
- Hotels with Free Parking in Otay Mesa
- Beach Hotels in Otay Mesa
- Family Hotels in Otay Mesa
- Winery Hotels in Otay Mesa
- Hotels with Hot Tubs in Otay Mesa
- Casinos in Otay Mesa
- Resorts & Hotels with Spas in Otay Mesa
- Hotels with smoking rooms in Otay Mesa
- Luxury Hotels in Otay Mesa
Top Points of Interests in Otay Mesa
- Hotels near San Diego Zoo
- Hotels near San Diego Convention Center
- Hotels near Mission Bay
- Hotels near San Ysidro Border Crossing
- Hotels near Balboa Park
- Hotels near Mission Beach
- Hotels near Petco Park
- Hotels near San Diego State University
- Hotels near Hotel Circle
- Hotels near Naval Base San Diego
- Hotels near USS Midway Museum
- Hotels near Marine Corps Recruit Depot
- Hotels near Port of San Diego
- Hotels near Coronado Beach
- Hotels near Hotel del Coronado
- Hotels near University of San Diego
- Hotels near B Street Cruise Ship Terminal
- Hotels near Mission Beach Boardwalk
- Hotels near Seaport Village
- Hotels near Naval Base Coronado
Cities near Otay Mesa
- San Diego Hotels (15.34 mi)
- Coronado Hotels (14.99 mi)
- Chula Vista Hotels (8.51 mi)
- Rosarito Hotels (14.31 mi)
- Playas de Rosarito Hotels (21.71 mi)
- Coronado Island Hotels (16.04 mi)
- El Cajon Hotels (16.26 mi)
- Southern California Hotels (91.04 mi)
- National City Hotels (10.98 mi)
- La Mesa Hotels (14.67 mi)
- Imperial Beach Hotels (8.3 mi)
- San Ysidro Hotels (4.08 mi)
- Alpine Hotels (22.51 mi)
- Tecate Hotels (19.72 mi)
- Santee Hotels (19.26 mi)
- Spring Valley Hotels (12.88 mi)
Car Rentals Near Otay Mesa
- Car rentals in San Diego
- Car rentals in Coronado
- Car rentals in Chula Vista
- Car rentals in Rosarito
- Car rentals in Playas de Rosarito
- Car rentals in Coronado Island
- Car rentals in El Cajon
- Car rentals in Southern California
- Car rentals in National City
- Car rentals in La Mesa
- Car rentals in Imperial Beach
- Car rentals in San Ysidro
- Car rentals in Alpine
- Car rentals in Tecate
- Car rentals in Santee
- Car rentals in Spring Valley
Top Historic Hotel Destinations
- Pasadena Historic Hotel
- Downtown Minneapolis Historic Hotel
- Downtown Boise Historic Hotel
- Brooklyn Historic Hotel
- Downtown Seattle Historic Hotel
- Downtown St Louis Historic Hotel
- Detroit Historic Hotel
- Downtown Nashville Historic Hotel
- Minnesota Historic Hotel
- Downtown Dallas Historic Hotel
- Downtown Edmonton Historic Hotel
- Oklahoma Historic Hotel
- Downtown Omaha Historic Hotel
- Downtown Kansas City Historic Hotel
- Downtown Salt Lake City Historic Hotel
- Raleigh Historic Hotel
- Downtown Reno Historic Hotel
- Baltimore Historic Hotel
- Tampa Historic Hotel
- Atlanta Historic Hotel
Top Booked Hotels in Otay Mesa
- The Dana on Mission Bay
- Omni San Diego Hotel
- Hard Rock Hotel San Diego
- Hyatt Regency Mission Bay Spa and Marina
- Comfort Inn Sea World Area
- Sheraton Mission Valley San Diego Hotel
- Wyndham San Diego Bayside
- Handlery Hotel
- San Diego Marriott Gaslamp Quarter
- Sheraton San Diego Resort
- The Sofia Hotel
- Humphreys Half Moon Inn
- Kings Inn San Diego
- The Horton Grand, Downtown/Gaslamp Quarter
- Bay Club Hotel & Marina