Search for Cheap Deals onSpa Resort Hotels in Otay Mesa
Check Last Minute Otay Mesa Hotel Deals
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Featured Otay Mesa Resorts & Hotels with Spas
Quality Suites San Diego Otay Mesa
2351 Otay Center Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Otay Mesa
Top Points of Interests in Otay Mesa
- Hotels near San Diego Zoo
- Hotels near San Diego Convention Center
- Hotels near Mission Bay
- Hotels near San Ysidro Border Crossing
- Hotels near Balboa Park
- Hotels near Mission Beach
- Hotels near Petco Park
- Hotels near San Diego State University
- Hotels near Hotel Circle
- Hotels near Naval Base San Diego
- Hotels near USS Midway Museum
- Hotels near Marine Corps Recruit Depot
- Hotels near Port of San Diego
- Hotels near Coronado Beach
- Hotels near Hotel del Coronado
- Hotels near University of San Diego
- Hotels near B Street Cruise Ship Terminal
- Hotels near Mission Beach Boardwalk
- Hotels near Seaport Village
- Hotels near Naval Base Coronado
Cities near Otay Mesa
- San Diego Hotels (15.34 mi)
- Coronado Hotels (14.99 mi)
- Chula Vista Hotels (8.51 mi)
- Playas de Rosarito Hotels (21.71 mi)
- Rosarito Hotels (14.31 mi)
- Coronado Island Hotels (16.04 mi)
- El Cajon Hotels (16.26 mi)
- Southern California Hotels (91.04 mi)
- National City Hotels (10.98 mi)
- La Mesa Hotels (14.67 mi)
- Imperial Beach Hotels (8.3 mi)
- San Ysidro Hotels (4.08 mi)
- Alpine Hotels (22.51 mi)
- Tecate Hotels (19.72 mi)
- Santee Hotels (19.26 mi)
- Spring Valley Hotels (12.88 mi)
- Lakeside Hotels (20.78 mi)
- Bonita Hotels (7.71 mi)
- San Diego Coast Hotels (24.31 mi)
- Jamul Hotels (12.26 mi)
Car Rentals Near Otay Mesa
- Car rentals in San Diego
- Car rentals in Coronado
- Car rentals in Chula Vista
- Car rentals in Playas de Rosarito
- Car rentals in Rosarito
- Car rentals in Coronado Island
- Car rentals in El Cajon
- Car rentals in Southern California
- Car rentals in National City
- Car rentals in La Mesa
- Car rentals in Imperial Beach
- Car rentals in San Ysidro
- Car rentals in Alpine
- Car rentals in Tecate
- Car rentals in Santee
- Car rentals in Spring Valley
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels