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Featured Otay Mesa Resorts & Hotels with Spas
Quality Suites San Diego Otay Mesa
2351 Otay Center Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Points of Interests in Otay Mesa
- Hotels near San Diego Zoo
- Hotels near San Diego Convention Center
- Hotels near San Ysidro Border Crossing
- Hotels near Mission Bay
- Hotels near Petco Park
- Hotels near Mission Beach
- Hotels near Naval Base San Diego
- Hotels near Balboa Park
- Hotels near Marine Corps Recruit Depot
- Hotels near Hotel Circle
- Hotels near San Diego State University
- Hotels near Port of San Diego
- Hotels near Hotel del Coronado
- Hotels near University of San Diego
- Hotels near B Street Cruise Ship Terminal
- Hotels near Las Americas Premium Outlets
- Hotels near USS Midway Museum
- Hotels near Coronado Beach
- Hotels near Seaport Village
- Hotels near Naval Base Coronado
Cities near Otay Mesa
- San Diego Hotels (15.34 mi)
- Coronado Hotels (14.99 mi)
- Chula Vista Hotels (8.51 mi)
- Playas de Rosarito Hotels (21.71 mi)
- Rosarito Hotels (14.31 mi)
- El Cajon Hotels (16.26 mi)
- Coronado Island Hotels (16.04 mi)
- National City Hotels (10.98 mi)
- Southern California Hotels (91.04 mi)
- San Ysidro Hotels (4.08 mi)
- La Mesa Hotels (14.67 mi)
- Alpine Hotels (22.51 mi)
- Imperial Beach Hotels (8.3 mi)
- Tecate Hotels (19.72 mi)
- Santee Hotels (19.26 mi)
- Spring Valley Hotels (12.88 mi)
- Bonita Hotels (7.71 mi)
- Lakeside Hotels (20.78 mi)
- Lemon Grove Hotels (13.08 mi)
- San Diego Coast Hotels (24.31 mi)
Car Rentals Near Otay Mesa
- Car rentals in San Diego
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- Car rentals in Chula Vista
- Car rentals in Playas de Rosarito
- Car rentals in Rosarito
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- Car rentals in Coronado Island
- Car rentals in National City
- Car rentals in Southern California
- Car rentals in San Ysidro
- Car rentals in La Mesa
- Car rentals in Alpine
- Car rentals in Imperial Beach
- Car rentals in Tecate
- Car rentals in Santee
- Car rentals in Spring Valley
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels
Top Booked Hotels in Otay Mesa
- Wyndham Garden San Diego Near SeaWorld
- Manchester Grand Hyatt San Diego
- Wyndham San Diego Bayside
- Best Western Seven Seas
- The Dana on Mission Bay
- San Diego Mission Bay Resort
- Paradise Point Resort & Spa
- Days Inn by Wyndham San Diego Hotel Circle
- Comfort Inn Sea World Area
- Hyatt Regency Mission Bay Spa and Marina
- Hilton San Diego Mission Valley
- Best Western Plus Marina Gateway Hotel