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Featured Luxury Otay Mesa
Quality Suites San Diego Otay Mesa
2351 Otay Center Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Otay Mesa
- Hotels with a Pool in Otay Mesa
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- Hotels with Hot Tubs in Otay Mesa
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- Resorts & Hotels with Spas in Otay Mesa
- Hotels with smoking rooms in Otay Mesa
Top Points of Interests in Otay Mesa
- Hotels near Cross Border Xpress
- Hotels near San Diego Zoo
- Hotels near Mission Bay
- Hotels near San Diego Convention Center
- Hotels near San Ysidro Border Crossing
- Hotels near Mission Beach
- Hotels near Balboa Park
- Hotels near Petco Park
- Hotels near Hotel Circle
- Hotels near Naval Base San Diego
- Hotels near San Diego State University
- Hotels near Port of San Diego
- Hotels near Marine Corps Recruit Depot
- Hotels near USS Midway Museum
- Hotels near Naval Base Coronado
- Hotels near Coronado Beach
- Hotels near Seaport Village
- Hotels near Hotel del Coronado
- Hotels near University of San Diego
- Hotels near Mission Beach Boardwalk
Cities near Otay Mesa
- San Diego Hotels (15.34 mi)
- Chula Vista Hotels (8.51 mi)
- Coronado Hotels (14.99 mi)
- Playas de Rosarito Hotels (21.71 mi)
- Rosarito Hotels (14.31 mi)
- Coronado Island Hotels (16.04 mi)
- El Cajon Hotels (16.26 mi)
- Southern California Hotels (91.04 mi)
- National City Hotels (10.98 mi)
- La Mesa Hotels (14.67 mi)
- Imperial Beach Hotels (8.3 mi)
- Alpine Hotels (22.51 mi)
- San Ysidro Hotels (4.08 mi)
- Tecate Hotels (19.72 mi)
- Santee Hotels (19.26 mi)
- Spring Valley Hotels (12.88 mi)
- Lakeside Hotels (20.78 mi)
- Bonita Hotels (7.71 mi)
- San Diego Coast Hotels (24.31 mi)
- Lemon Grove Hotels (13.08 mi)
Car Rentals Near Otay Mesa
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- Car rentals in Southern California
- Car rentals in National City
- Car rentals in La Mesa
- Car rentals in Imperial Beach
- Car rentals in Alpine
- Car rentals in San Ysidro
- Car rentals in Tecate
- Car rentals in Santee
- Car rentals in Spring Valley
Top Luxury Hotel Destinations
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Top Booked Hotels in Otay Mesa
- Wyndham San Diego Bayside
- Marriott Marquis San Diego Marina
- Handlery Hotel
- Manchester Grand Hyatt San Diego
- Hyatt Regency Mission Bay Spa and Marina
- Kings Inn San Diego
- The Little Italy Hotel Downtown San Diego
- Comfort Inn Sea World Area
- The Dana on Mission Bay
- Sheraton San Diego Resort
- San Diego Mission Bay Resort
- Hilton San Diego Mission Valley