Search for Cheap Deals on
4 Star Hotels in Ohio River Valley

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!


Featured 4 Star Ohio River Valley Hotels

Sonesta Columbus Downtown
4 out of 5
  • 3 hours drive from Ark Encounter
The price is $197 per night from Mar 17 to Mar 18
$197
includes taxes & fees
Mar 17 - Mar 18
Book a stay at this business-friendly hotel in Columbus. Enjoy breakfast (surcharge), a 24-hour fitness center, and WiFi (surcharge). Our guests praise the restaurant ...
Sonesta Columbus Downtown
Omni Louisville Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 3 hours drive from Ark Encounter
The price is $229 per night from Feb 25 to Feb 26
$229
includes taxes & fees
Feb 25 - Feb 26
Stay at this 4-star spa hotel in Louisville. Enjoy a full-service spa, 3 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
Omni Louisville Hotel
Galt House Hotel Trademark Collection by Wyndham
4 out of 5
Fully refundableReserve now, pay when you stay
  • 3 hours drive from Ark Encounter
The price is $171 per night from Feb 26 to Feb 27
$171
includes taxes & fees
Feb 26 - Feb 27
Book a stay at this spa hotel in Louisville. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the restaurant and the helpful staff in ...
Galt House Hotel Trademark Collection by Wyndham
Save an average of 15% on thousands of hotels when you're signed in
Omni Severin Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 2 hours drive from Ark Encounter
The price is $168 per night from Mar 9 to Mar 10
$168
includes taxes & fees
Mar 9 - Mar 10
Stay at this 4-star business-friendly hotel in Indianapolis. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful ...
Omni Severin Hotel
I Hotel And Illinois Conference Center
4 out of 5
Fully refundableReserve now, pay when you stay
The price is $123 per night from Mar 2 to Mar 3
$123
includes taxes & fees
Mar 2 - Mar 3
Stay at this 4-star family-friendly hotel in Champaign. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
I Hotel And Illinois Conference Center
Ironworks Hotel Indy
4 out of 5
Fully refundableReserve now, pay when you stay
  • 3 hours drive from Ark Encounter
The price is $233 per night from Feb 23 to Feb 24
$233
includes taxes & fees
Feb 23 - Feb 24
Stay at this 4-star business-friendly hotel in Indianapolis. Enjoy free WiFi, free parking, and 4 restaurants. Our guests praise the helpful staff and the clean ...
Ironworks Hotel Indy
The Westin Cincinnati
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Ark Encounter
The price is $178 per night from Feb 21 to Feb 22
$178
includes taxes & fees
Feb 21 - Feb 22
Book a stay at this business-friendly hotel in Cincinnati. Enjoy breakfast (surcharge), parking (surcharge), and a 24-hour front desk. Our guests praise the ...
The Westin Cincinnati
JW Marriott Indianapolis
4 out of 5
Fully refundableReserve now, pay when you stay
  • 2 hours drive from Ark Encounter
The price is $198 per night from Mar 9 to Mar 10
$198
includes taxes & fees
Mar 9 - Mar 10
Stay at this 4-star business-friendly hotel in Indianapolis. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests ...
JW Marriott Indianapolis
Sheraton Indianapolis Hotel at Keystone Crossing
4 out of 5
Fully refundableReserve now, pay when you stay
  • 3 hours drive from Ark Encounter
The price is $109 per night from Feb 23 to Feb 24
$109
includes taxes & fees
Feb 23 - Feb 24
Stay at this 4-star business-friendly hotel in Indianapolis. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
Sheraton Indianapolis Hotel at Keystone Crossing
Hyatt Regency Cincinnati
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Ark Encounter
The price is $161 per night from Feb 28 to Mar 1
$161
includes taxes & fees
Feb 28 - Mar 1
Stay at this 4-star business-friendly hotel in Cincinnati. Enjoy free WiFi, breakfast (surcharge), and a health club. Our guests praise the helpful staff and ...
Hyatt Regency Cincinnati
Hilton Cincinnati Netherland Plaza
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Ark Encounter
The price is $148 per night from Mar 17 to Mar 18
$148
includes taxes & fees
Mar 17 - Mar 18
Book a stay at this historic hotel in Cincinnati. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Hilton Cincinnati Netherland Plaza
Hilton Columbus Downtown
4 out of 5
Fully refundableReserve now, pay when you stay
  • 3 hours drive from Ark Encounter
The price is $189 per night from Mar 9 to Mar 10
$189
includes taxes & fees
Mar 9 - Mar 10
Stay at this 4-star business-friendly hotel in Columbus. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the helpful ...
Hilton Columbus Downtown
Don't see what you're looking for?
See all available properties in Ohio River Valley
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in Ohio River Valley

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in Ohio River Valley for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in Ohio River Valley as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag Ohio River Valley 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in Ohio River Valley starting at $109 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded Ohio River Valley 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.