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Featured Ohio River Valley Resorts & Hotels with Spas
![Breckinridge Inn & Convention Center](https://images.trvl-media.com/lodging/1000000/920000/912200/912160/ceb5116d_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Breckinridge Inn & Convention Center
Breckenridge Lane, 2800, Louisville, KY
Book a stay at this business-friendly hotel in Louisville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Louisville Mega Cavern ...
![The Grand Resort](https://images.trvl-media.com/lodging/1000000/10000/6000/5940/ae0379b8_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
The Grand Resort
9519 East Market Street, Warren, OH
Stay at this 4-star golf hotel in Warren. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions ...
![Hilton Columbus/Polaris](https://images.trvl-media.com/lodging/3000000/2080000/2070600/2070598/eaadcf91_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Hilton Columbus/Polaris
8700 Lyra Dr, Columbus, OH
Stay at this 4-star business-friendly hotel in Columbus. Enjoy free WiFi, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful staff ...
![Conrad Indianapolis](https://images.trvl-media.com/lodging/2000000/1290000/1287500/1287480/8545ec98_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Conrad Indianapolis
50 W Washington St., Indianapolis, IN
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Indianapolis. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
![21c Museum Hotel Cincinnati](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/5b64e900_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
21c Museum Hotel Cincinnati
609 Walnut St, Cincinnati, OH
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Cincinnati. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the clean ...
![Marriott Lexington Griffin Gate Golf Resort & Spa](https://images.trvl-media.com/lodging/1000000/20000/15900/15892/7b2897b8_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Marriott Lexington Griffin Gate Golf Resort & Spa
1800 Newtown Pike, Lexington, KY
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury resort in Lexington. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff ...
![Country Inn & Suites by Radisson, Cincinnati Airport, KY](https://images.trvl-media.com/lodging/1000000/810000/805800/805705/821abc4d_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Country Inn & Suites by Radisson, Cincinnati Airport, KY
759 Petersburg Road, Hebron, KY
Fully refundable
Stay at this 3.5-star hotel in Hebron. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the helpful staff in ...
![Quality Inn](https://images.trvl-media.com/lodging/1000000/10000/2300/2219/e1557513_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Quality Inn
2055 E Lincoln Way, Wooster, OH
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Wooster. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
![Country Inn & Suites by Radisson, Louisville South, KY](https://images.trvl-media.com/lodging/1000000/800000/791700/791609/1f9147d9_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Country Inn & Suites by Radisson, Louisville South, KY
400 Paroquet Springs Drive, Shepherdsville, KY
Fully refundable
Book a stay at this business-friendly hotel in Shepherdsville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
![Kent State University Hotel and Conference Center](https://images.trvl-media.com/lodging/7000000/6370000/6369200/6369156/8bee8804_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Kent State University Hotel and Conference Center
215 S. Depeyster Street, Kent, OH
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Kent. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
![Belterra Casino Resort](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/04047b8f_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Belterra Casino Resort
777 Belterra Drive, Florence, IN
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star golf hotel in Florence. Enjoy an outdoor pool, 3 restaurants, and a golf course. Our guests praise the helpful staff and the clean rooms ...
![Best Western Wapakoneta Inn](https://images.trvl-media.com/lodging/1000000/560000/551200/551152/d530507c_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Best Western Wapakoneta Inn
1008 Lunar Drive, Wapakoneta, OH
Fully refundableReserve now, pay when you stay
Stay at this hotel in Wapakoneta. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Hotel Options in Ohio River Valley
- Hotels with Free Parking in Ohio River Valley
- Family Hotels in Ohio River Valley
- Hotels with a Pool in Ohio River Valley
- Pet-friendly Hotels in Ohio River Valley
- Hotels with an Indoor Pool in Ohio River Valley
- Historic Hotels in Ohio River Valley
- Hotels with Hot Tubs in Ohio River Valley
- Luxury Hotels in Ohio River Valley
- Hotel Wedding Venues in Ohio River Valley
- Winery Hotels in Ohio River Valley
Ohio River Valley Neighborhoods
- Downtown Indianapolis Hotels (65.08 mi)
- Downtown Louisville Hotels (115.06 mi)
- Downtown Columbus Hotels (103.14 mi)
- Downtown Cincinnati Hotels (52.99 mi)
- Polaris Hotels (106.37 mi)
- Downtown Lexington Hotels (122.98 mi)
- Near Eastside Hotels (62.21 mi)
- Norwood Hotels (50.55 mi)
- West Main Historic District Hotels (115.16 mi)
- Short North Hotels (103.23 mi)
- Worthington Hotels (103.68 mi)
- Over-the-Rhine Hotels (52.28 mi)
- University District Hotels (103.18 mi)
- Speedway Hotels (69.68 mi)
- Castleton Hotels (59.54 mi)
- Jeffersontown Hotels (115.5 mi)
- Old Louisville Hotels (116.42 mi)
- German Village Hotels (103.64 mi)
- Near Southside Hotels (64.8 mi)
Top Points of Interests in Ohio River Valley
- Hotels near Ark Encounter
- Hotels near Kings Island
- Hotels near Ohio State University
- Hotels near Lucas Oil Stadium
- Hotels near Indianapolis Motor Speedway
- Hotels near University of Illinois at Urbana-Champaign
- Hotels near Indiana Convention Center
- Hotels near Kentucky Exposition Center
- Hotels near Hocking Hills State Park
- Hotels near Purdue University
- Hotels near Great American Ball Park
- Hotels near Indiana University Bloomington
- Hotels near Greater Columbus Convention Center
- Hotels near University of Cincinnati
- Hotels near Gainbridge Fieldhouse
- Hotels near Children's Museum of Indianapolis
- Hotels near University of Kentucky
- Hotels near Paycor Stadium
- Hotels near Newport Aquarium
- Hotels near Easton Town Center
Cities near Ohio River Valley
- Logan Hotels (135.63 mi)
- Rockbridge Hotels (129.18 mi)
- Erie Hotels (299.93 mi)
- Sandusky Hotels (163.51 mi)
- Bloomington Hotels (95.49 mi)
- South Bend Hotels (147.02 mi)
- Dayton Hotels (39.61 mi)
- Michigan City Hotels (167.12 mi)
- Ellicottville Hotels (368.37 mi)
- Marblehead Hotels (166.82 mi)
- Champaign Hotels (176.38 mi)
- Nashville Hotels (80.7 mi)
- Upstate New York Hotels (530.13 mi)
- Evansville Hotels (188.81 mi)
- Lancaster Hotels (124.24 mi)
- Akron Hotels (200.4 mi)
- Millersburg Hotels (167.72 mi)
Car Rentals Near Ohio River Valley
- Car rentals in Logan
- Car rentals in Rockbridge
- Car rentals in Erie
- Car rentals in Sandusky
- Car rentals in Bloomington
- Car rentals in South Bend
- Car rentals in Dayton
- Car rentals in Michigan City
- Car rentals in Ellicottville
- Car rentals in Marblehead
- Car rentals in Champaign
- Car rentals in Nashville
- Car rentals in Upstate New York
- Car rentals in Evansville
- Car rentals in Lancaster
- Car rentals in Akron
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels
Top Booked Hotels in Ohio River Valley
- Omni Louisville Hotel
- Galt House Hotel Trademark Collection by Wyndham
- Sonesta Columbus Downtown
- Omni Severin Hotel
- Wyndham Columbus
- Ironworks Hotel Indy
- JW Marriott Indianapolis
- Radisson Hotel Cincinnati Riverfront
- Crowne Plaza Louisville Airport Expo Ctr, an IHG Hotel
- Marriott Indianapolis Downtown
- Wyndham Indianapolis Airport
- Radisson Hotel Louisville North