Search for Cheap Deals on4 Star Hotels in Otay Mesa West
Photo by Leonardo De Leon
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Featured 4 Star Otay Mesa West Hotels

Fully refundableReserve now, pay when you stay
The price is $176 per night from May 11 to May 12
$176
per night
May 11 - May 12
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...

Fully refundableReserve now, pay when you stay
The price is $266 per night from May 26 to May 27
$266
per night
May 26 - May 27
Stay at this 4-star beach hotel in Coronado. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...

Fully refundableReserve now, pay when you stay
The price is $285 per night from May 11 to May 12
$285
per night
May 11 - May 12
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
Save an average of 15% on thousands of hotels when you're signed in

Fully refundableReserve now, pay when you stay
The price is $194 per night from May 11 to May 12
$194
per night
May 11 - May 12
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...

Fully refundableReserve now, pay when you stay
The price is $236 per night from May 12 to May 13
$236
per night
May 12 - May 13
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 5 restaurants, and a marina. Our guests praise the pool and the restaurant in ...

The price is $301 per night from May 25 to May 26
$301
per night
May 25 - May 26
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our ...

Fully refundableReserve now, pay when you stay
The price is $144 per night from May 11 to May 12
$144
per night
May 11 - May 12
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...

Fully refundableReserve now, pay when you stay
The price is $234 per night from May 23 to May 24
$234
per night
May 23 - May 24
Book a stay at this eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...

Fully refundableReserve now, pay when you stay
The price is $259 per night from May 6 to May 7
$259
per night
May 6 - May 7
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...

Fully refundableReserve now, pay when you stay
The price is $109 per night from May 11 to May 12
$109
per night
May 11 - May 12
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular ...

Fully refundableReserve now, pay when you stay
The price is $369 per night from May 23 to May 24
$369
per night
May 23 - May 24
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...

Fully refundableReserve now, pay when you stay
The price is $231 per night from May 6 to May 7
$231
per night
May 6 - May 7
Book a stay at this business-friendly hotel in San Diego. Enjoy 2 bars/lounges, a nightclub, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Hotel Options in Otay Mesa West
Popular Otay Mesa West Hotels
- San Diego Mission Bay Resort
- Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
- Wyndham San Diego Bayside
- The Dana on Mission Bay
- Hilton San Diego Mission Valley
- Handlery Hotel
- Paradise Point Resort & Spa
- Humphreys Half Moon Inn
- Kings Inn San Diego
- Bahia Resort Hotel
- Wyndham Garden San Diego Near SeaWorld
Top Attractions in Otay Mesa West
- Hotels near San Diego Zoo (12.29 mi)
- Hotels near San Diego Convention Center (10.87 mi)
- Hotels near Mission Bay (17.06 mi)
- Hotels near Petco Park (10.76 mi)
- Hotels near Mission Beach (17.63 mi)
- Hotels near San Ysidro Border Crossing (2.74 mi)
- Hotels near San Diego State University (13.58 mi)
- Hotels near Balboa Park (11.88 mi)
- Hotels near Hotel Circle (14.43 mi)
- Hotels near Naval Base San Diego (7.94 mi)
- Hotels near Marine Corps Recruit Depot (13.97 mi)
- Hotels near Coronado Beach (10.63 mi)
- Hotels near Port of San Diego (11.85 mi)
- Hotels near University of San Diego (15.6 mi)
- Hotels near USS Midway Museum (11.73 mi)
- Hotels near Seaport Village (11.3 mi)
- Hotels near Mission Beach Boardwalk (17.18 mi)
- Hotels near Hotel del Coronado (10.11 mi)
- Hotels near Naval Base Coronado (12.2 mi)
- Hotels near B Street Cruise Ship Terminal (11.92 mi)
Nearby Cities
- San Diego Hotels (11.38 mi)
- La Jolla Hotels (21.67 mi)
- Coronado Hotels (10.58 mi)
- Chula Vista Hotels (4.65 mi)
- Playas de Rosarito Hotels (24.36 mi)
- Rosarito Hotels (14.61 mi)
- Coronado Island Hotels (11.64 mi)
- El Cajon Hotels (15.92 mi)
- Southern California Hotels (89.06 mi)
- National City Hotels (7.41 mi)
- La Mesa Hotels (13.26 mi)
- Imperial Beach Hotels (3.44 mi)
Recommended cities for you
- Las Vegas Hotels
- New York Hotels
- Orlando Hotels
- Los Angeles Hotels
- Miami Hotels
- San Francisco Hotels
- New Orleans Hotels
- Chicago Hotels
- Fort Lauderdale Hotels
- Boston Hotels
- Honolulu Hotels
- San Diego Hotels
- Washington Hotels
- Toronto Hotels
- Anaheim Hotels
- Atlanta Hotels
- Nashville Hotels
- Seattle Hotels
- Phoenix Hotels
- Myrtle Beach Hotels
Car Rentals Near Otay Mesa West
- Car rentals in San Diego
- Car rentals in La Jolla
- Car rentals in Coronado
- Car rentals in Chula Vista
- Car rentals in Playas de Rosarito
- Car rentals in Rosarito
- Car rentals in Coronado Island
- Car rentals in El Cajon
- Car rentals in Southern California
- Car rentals in National City
- Car rentals in La Mesa
- Car rentals in Imperial Beach
- Car rentals in San Ysidro
- Car rentals in Santee
- Car rentals in Alpine
- Car rentals in San Diego Coast