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Featured 4 Star Uptown Hotels

Fully refundableReserve now, pay when you stay
The price is $129 per night from Apr 19 to Apr 20
$129
includes taxes & fees
Apr 19 - Apr 20
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...

Fully refundableReserve now, pay when you stay
The price is $201 per night from May 4 to May 5
$201
includes taxes & fees
May 4 - May 5
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...

Fully refundableReserve now, pay when you stay
The price is $126 per night from May 7 to May 8
$126
includes taxes & fees
May 7 - May 8
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
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Fully refundableReserve now, pay when you stay
The price is $182 per night from Apr 20 to Apr 21
$182
includes taxes & fees
Apr 20 - Apr 21
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...

Fully refundableReserve now, pay when you stay
The price is $195 per night from Apr 20 to Apr 21
$195
includes taxes & fees
Apr 20 - Apr 21
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...

Fully refundableReserve now, pay when you stay
The price is $168 per night from Apr 20 to Apr 21
$168
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this eco-certified hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...

Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the pool and the ...

Fully refundableReserve now, pay when you stay
The price is $120 per night from Apr 27 to Apr 28
$120
includes taxes & fees
Apr 27 - Apr 28
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free breakfast, a fitness center, and WiFi (surcharge). Our guests praise the breakfast and the ...

Fully refundableReserve now, pay when you stay
The price is $165 per night from Apr 27 to Apr 28
$165
includes taxes & fees
Apr 27 - Apr 28
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...

Fully refundableReserve now, pay when you stay
The price is $176 per night from Apr 20 to Apr 21
$176
includes taxes & fees
Apr 20 - Apr 21
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...

The price is $174 per night from Apr 20 to Apr 21
$174
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this luxury hotel in St. Louis. Enjoy breakfast (surcharge), 24-hour room service, and valet parking (surcharge). Our guests praise the helpful ...

Fully refundableReserve now, pay when you stay
The price is $136 per night from Apr 27 to Apr 28
$136
includes taxes & fees
Apr 27 - Apr 28
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), a fitness center, and valet parking (surcharge). Our guests praise the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Attractions in Uptown
- Hotels near World's Largest Catsup Bottle (0.51 mi)
- Hotels near Kruta Bakery (0.45 mi)
- Hotels near Enterprise Center (11.75 mi)
- Hotels near Busch Stadium (11.33 mi)
- Hotels near St. Louis Union Station (11.95 mi)
- Hotels near Gateway Arch (10.86 mi)
- Hotels near St. Louis Zoo (16.31 mi)
- Hotels near Washington University in St. Louis (17.23 mi)
- Hotels near Forest Park (15.61 mi)
- Hotels near City Museum (11.55 mi)
- Hotels near Barnes Jewish Hospital (14.94 mi)
- Hotels near Dome at America’s Center (10.94 mi)
- Hotels near St. Louis University (13.23 mi)
- Hotels near Fox Theater (13.14 mi)
- Hotels near America's Center Convention Complex (11.09 mi)
- Hotels near Mississippi River (87.1 mi)
- Hotels near Anheuser-Busch Brewery (12.78 mi)
- Hotels near Horseshoe St. Louis Casino (10.71 mi)
- Hotels near St. Louis Aquarium at Union Station (11.99 mi)
- Hotels near Missouri River (783.89 mi)
Nearby Cities
- O'Fallon Hotels (6.7 mi)
- Fairview Heights Hotels (5.15 mi)
- Collinsville Hotels (0.35 mi)
- Edwardsville Hotels (9.2 mi)
- East St. Louis Hotels (9.39 mi)
- Alton Hotels (18.64 mi)
- Ozarks Hotels (171.91 mi)
- Richmond Heights Hotels (17.92 mi)
- Belleville Hotels (10.13 mi)
- Brentwood Hotels (19.63 mi)
- Southern Illinois Hotels (65.36 mi)
- Florissant Hotels (19.77 mi)
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