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4 Star Hotels in Uptown

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Featured 4 Star Uptown Hotels

Hyatt Regency St. Louis at The Arch
4 out of 5
Fully refundableReserve now, pay when you stay
  • 21 min drive from World's Largest Catsup Bottle
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
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Hyatt Regency St. Louis at The Arch
Moonrise Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 30 min drive from World's Largest Catsup Bottle
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
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Moonrise Hotel
21C Museum Hotel St Louis
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 22 min drive from World's Largest Catsup Bottle
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
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21C Museum Hotel St Louis
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St. Louis Union Station Hotel, Curio Collection by Hilton
4 out of 5
Fully refundableReserve now, pay when you stay
  • 23 min drive from World's Largest Catsup Bottle
Book a stay at this historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 7 restaurants. Our guests praise the helpful staff and the clean rooms ...
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St. Louis Union Station Hotel, Curio Collection by Hilton
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 21 min drive from World's Largest Catsup Bottle
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the bar and the helpful ...
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Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Marriott St. Louis Grand
4 out of 5
Fully refundableReserve now, pay when you stay
  • 21 min drive from World's Largest Catsup Bottle
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise ...
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Marriott St. Louis Grand
Live by Loews - St.Louis
4 out of 5
  • 22 min drive from World's Largest Catsup Bottle
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
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Live by Loews - St.Louis
Hilton St. Louis at the Ballpark
4 out of 5
Fully refundableReserve now, pay when you stay
  • 21 min drive from World's Largest Catsup Bottle
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy 3 restaurants, 3 bars/lounges, and a rooftop terrace. Our guests praise the clean rooms in our ...
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Hilton St. Louis at the Ballpark
Le Méridien St. Louis Clayton
4 out of 5
  • 34 min drive from World's Largest Catsup Bottle
Book a stay at this eco-certified hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
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Le Méridien St. Louis Clayton
The Westin St. Louis
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 22 min drive from World's Largest Catsup Bottle
Book a stay at this luxury hotel in St. Louis. Enjoy breakfast (surcharge), 24-hour room service, and valet parking (surcharge). Our guests praise the helpful ...
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The Westin St. Louis
River City Casino & Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 37 min drive from World's Largest Catsup Bottle
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
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River City Casino & Hotel
The Royal Sonesta Chase Park Plaza St. Louis
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 28 min drive from World's Largest Catsup Bottle
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
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The Royal Sonesta Chase Park Plaza St. Louis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.