Search for Cheap Deals on4 Star Hotels in Otay Mesa West
Photo by Leonardo De Leon
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Featured 4 Star Otay Mesa West Hotels
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
Fully refundable
Book a stay at this business-friendly hotel in San Diego. Enjoy 2 restaurants, 3 bars/lounges, and a rooftop terrace. Our guests praise the helpful staff and ...
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Save an average of 15% on thousands of hotels when you're signed in
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Fully refundableReserve now, pay when you stay
Book a stay at this beach resort in Coronado. Enjoy free WiFi, 6 restaurants, and a private beach. Our guests praise the helpful staff in our reviews. Popular ...
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
Fully refundableReserve now, pay when you stay
Stay at this 4-star family-friendly hotel in San Diego. Enjoy 2 outdoor pools, 5 restaurants, and a marina. Our guests praise the pool and the helpful staff ...
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Hotel Options in Otay Mesa West
Popular Otay Mesa West Hotels
- Hotel del Coronado, Curio Collection by Hilton
- Hilton San Diego Mission Valley
- Hampton Inn & Suites by Hilton San Diego SeaWorld
- Hard Rock Hotel San Diego
- Courtyard by Marriott San Diego Downtown Little Italy
- Pendry San Diego
- Wyndham San Diego Bayside
- Handlery Hotel
- The Dana on Mission Bay
- The DEXTRO Little Italy, BW Premier Collection
- Comfort Inn Sea World Area
Top Attractions in Otay Mesa West
- Hotels near San Diego Zoo (12.29 mi)
- Hotels near San Diego Convention Center (10.87 mi)
- Hotels near Mission Bay (17.06 mi)
- Hotels near San Ysidro Border Crossing (2.74 mi)
- Hotels near Petco Park (10.76 mi)
- Hotels near Port of San Diego (11.85 mi)
- Hotels near Balboa Park (11.88 mi)
- Hotels near Hotel Circle (14.43 mi)
- Hotels near Mission Beach (17.63 mi)
- Hotels near Marine Corps Recruit Depot (13.97 mi)
- Hotels near Naval Base San Diego (7.94 mi)
- Hotels near USS Midway Museum (11.73 mi)
- Hotels near Hotel del Coronado (10.11 mi)
- Hotels near Las Americas Premium Outlets (2.43 mi)
- Hotels near Coronado Beach (10.63 mi)
- Hotels near University of San Diego (15.6 mi)
- Hotels near B Street Cruise Ship Terminal (11.92 mi)
- Hotels near Seaport Village (11.3 mi)
- Hotels near San Diego State University (13.58 mi)
- Hotels near Sycuan Casino (19.4 mi)
Nearby Cities
- San Diego Hotels (11.38 mi)
- La Jolla Hotels (21.67 mi)
- Chula Vista Hotels (4.65 mi)
- Coronado Hotels (10.58 mi)
- Playas de Rosarito Hotels (24.36 mi)
- Rosarito Hotels (14.61 mi)
- El Cajon Hotels (15.92 mi)
- Coronado Island Hotels (11.64 mi)
- National City Hotels (7.41 mi)
- Southern California Hotels (89.06 mi)
- La Mesa Hotels (13.26 mi)
- San Ysidro Hotels (1.89 mi)