Search for Cheap Deals on
Luxury Hotels in Tenderloin

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!


Featured Luxury Tenderloin

The Clift Royal Sonesta San Francisco
The Clift Royal Sonesta San Francisco
4 out of 5
495 Geary St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this historic hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the bar and the ...
The Clift Royal Sonesta San Francisco
Hotel Spero, Vignette Collection, an IHG Hotel
Hotel Spero, Vignette Collection, an IHG Hotel
4 out of 5
405 Taylor St, San Francisco, CA
Stay at this 4-star hotel in San Francisco. Enjoy breakfast (surcharge), a 24-hour fitness center, and a 24-hour front desk. Our guests praise the restaurant ...
Hotel Spero, Vignette Collection, an IHG Hotel
Hotel Nikko San Francisco
Hotel Nikko San Francisco
4.5 out of 5
222 Mason St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in San Francisco. Enjoy free WiFi, a nightclub, and a rooftop terrace. Our guests praise the breakfast and the pool in our ...
Hotel Nikko San Francisco
Staypineapple, An Elegant Hotel, Union Square
Staypineapple, An Elegant Hotel, Union Square
4 out of 5
580 Geary St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Francisco. Enjoy free bicycles on site, a 24-hour front desk, and a business center. Our guests praise the helpful staff and the clean ...
Staypineapple, An Elegant Hotel, Union Square
Handlery Union Square Hotel
Handlery Union Square Hotel
3.5 out of 5
351 Geary St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
Handlery Union Square Hotel
Monarch Hotel
Monarch Hotel
2 out of 5
1015 Geary St, San Francisco, CA
Stay at this hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Popular attractions Oracle Park and Pier 39 are located ...
Monarch Hotel
Hotel Bijou
Hotel Bijou
4 out of 5
111 Mason Street, San Francisco, CA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free breakfast, a 24-hour front desk, and a business center. Our guests praise the helpful ...
Hotel Bijou
Adante Hotel
Adante Hotel
3 out of 5
610 Geary St, San Francisco, CA
Stay at this 3-star business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and valet parking (surcharge). Popular attractions Oracle Park ...
Adante Hotel
Parc 55 San Francisco - A Hilton Hotel
Parc 55 San Francisco - A Hilton Hotel
4 out of 5
55 Cyril Magnin St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 restaurants, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
Parc 55 San Francisco - A Hilton Hotel
The Marker Union Square San Francisco
The Marker Union Square San Francisco
4 out of 5
501 Geary St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this boutique hotel in San Francisco. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise ...
The Marker Union Square San Francisco
The Bartlett Hotel and Guesthouse
The Bartlett Hotel and Guesthouse
2.5 out of 5
240 O'Farrell St, San Francisco, CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Francisco. Enjoy free WiFi, laundry facilities, and cable TV channels. Our guests praise the clean rooms in our reviews. Popular attractions ...
The Bartlett Hotel and Guesthouse
Alexis Park Hotel
Alexis Park Hotel
2 out of 5
825 Polk Street, San Francisco, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...
Alexis Park Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.