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4 Star Hotels in Central United States

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Featured 4 Star Central United States Hotels

Embassy Suites by Hilton Chicago Downtown River North
4 out of 5
Fully refundableReserve now, pay when you stay
  • 18 hours drive from Great Smoky Mountains National Park
The price is $175 per night from Apr 30 to May 1
$175
includes taxes & fees
Apr 30 - May 1
Stay at this 4-star hotel in Chicago. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the pool in our reviews. ...
Embassy Suites by Hilton Chicago Downtown River North
The Westin Michigan Avenue Chicago
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 18 hours drive from Great Smoky Mountains National Park
The price is $200 per night from May 9 to May 10
$200
includes taxes & fees
May 9 - May 10
Stay at this 4.5-star luxury hotel in Chicago. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
The Westin Michigan Avenue Chicago
Bourbon Orleans Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 15 hours drive from Great Smoky Mountains National Park
The price is $167 per night from May 26 to May 27
$167
includes taxes & fees
May 26 - May 27
Book a stay at this historic hotel in New Orleans. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the pool and the bar in our ...
Bourbon Orleans Hotel
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Hilton Chicago O'Hare Airport
4 out of 5
Fully refundableReserve now, pay when you stay
  • 18 hours drive from Great Smoky Mountains National Park
The price is $253 per night from May 23 to May 24
$253
includes taxes & fees
May 23 - May 24
Stay at this 4-star business-friendly hotel in Chicago. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Hilton Chicago O'Hare Airport
The Westin Dallas Park Central
4 out of 5
Fully refundableReserve now, pay when you stay
  • 4 hours drive from Great Smoky Mountains National Park
The price is $119 per night from May 26 to May 27
$119
includes taxes & fees
May 26 - May 27
Stay at this 4-star business-friendly hotel in Dallas. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...
The Westin Dallas Park Central
Club Quarters Hotel Downtown, Houston
4 out of 5
Fully refundableReserve now, pay when you stay
  • 18 hours drive from Great Smoky Mountains National Park
The price is $137 per night from Apr 27 to Apr 28
$137
includes taxes & fees
Apr 27 - Apr 28
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
Club Quarters Hotel Downtown, Houston
Swissotel - Chicago
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 18 hours drive from Great Smoky Mountains National Park
The price is $235 per night from May 2 to May 3
$235
includes taxes & fees
May 2 - May 3
Book a stay at this eco-certified hotel in Chicago. Enjoy 2 bars/lounges, breakfast (surcharge), and 24-hour room service. Our guests praise the restaurant and ...
Swissotel - Chicago
Hyatt Regency O'Hare Chicago
4 out of 5
Fully refundableReserve now, pay when you stay
  • 18 hours drive from Great Smoky Mountains National Park
The price is $173 per night from May 19 to May 20
$173
includes taxes & fees
May 19 - May 20
Book a stay at this eco-certified hotel in Rosemont. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
Hyatt Regency O'Hare Chicago
Hyatt Regency Schaumburg Chicago
4 out of 5
Fully refundableReserve now, pay when you stay
  • 19 hours drive from Great Smoky Mountains National Park
The price is $137 per night from Apr 27 to Apr 28
$137
includes taxes & fees
Apr 27 - Apr 28
Stay at this 4-star business-friendly hotel in Schaumburg. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
Hyatt Regency Schaumburg Chicago
L7 Chicago by LOTTE
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 18 hours drive from Great Smoky Mountains National Park
The price is $212 per night from May 11 to May 12
$212
includes taxes & fees
May 11 - May 12
Book a stay at this boutique hotel in Chicago. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and ...
L7 Chicago by LOTTE
Crowne Plaza New Orleans French Qtr - Astor by IHG
4.5 out of 5
Fully refundable
  • 15 hours drive from Great Smoky Mountains National Park
The price is $143 per night from Apr 28 to Apr 29
$143
includes taxes & fees
Apr 28 - Apr 29
Stay at this 4.5-star luxury hotel in New Orleans. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the helpful ...
Crowne Plaza New Orleans French Qtr - Astor by IHG
River Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 18 hours drive from Great Smoky Mountains National Park
The price is $173 per night from May 11 to May 12
$173
includes taxes & fees
May 11 - May 12
Stay at this 4-star business-friendly hotel in Chicago. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and the clean ...
River Hotel
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4-star hotels in Central United States

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in Central United States for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in Central United States as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag Central United States 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in Central United States starting at $119 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded Central United States 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.