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Featured Tenderloin Family Hotels

Handlery Union Square Hotel

351 Geary St San Francisco CA

Fully refundableReserve now, pay when you stay

Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...

Hilton San Francisco Union Square

333 O'Farrell St. San Francisco CA

Fully refundableReserve now, pay when you stay

Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...

Parc 55 San Francisco - A Hilton Hotel

55 Cyril Magnin St San Francisco CA

Fully refundableReserve now, pay when you stay

Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 restaurants, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...

Hotel Spero, Vignette Collection by IHG

405 Taylor St San Francisco CA

Fully refundable

Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a 24-hour fitness center, and a 24-hour front desk. Our guests praise ...

Axiom Hotel

28 Cyril Magnin Street San Francisco CA

Fully refundableReserve now, pay when you stay

Book a stay at this family-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...

Alexis Park Hotel

825 Polk Street San Francisco CA

Fully refundableReserve now, pay when you stay

Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...

Adante Hotel

610 Geary St San Francisco CA

Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and valet parking (surcharge). Popular attractions Pier 39 and ...

The Marker Union Square San Francisco

501 Geary St San Francisco CA

Fully refundableReserve now, pay when you stay

Book a stay at this boutique hotel in San Francisco. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise ...

COVA Hotel

655 Ellis Street San Francisco CA

Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a rooftop terrace. Popular attractions Pier 39 and Golden ...

Hotel Nikko San Francisco

222 Mason St San Francisco CA

Fully refundableReserve now, pay when you stay

Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the breakfast and the pool in our reviews. ...

Hotel Bijou

111 Mason Street San Francisco CA

Fully refundableReserve now, pay when you stay

Stay at this hotel in San Francisco. Enjoy a 24-hour front desk, a business center, and concierge services. Our guests praise the helpful staff in our reviews. ...

Hotel G San Francisco

386 Geary Street San Francisco CA

Fully refundableReserve now, pay when you stay

Stay at this hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and parking (surcharge). Our guests praise the helpful staff and the clean ...

See all 4,653 properties in Tenderloin

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.